Fibroblast Growth Factor 6 (FGF6)
[Edit]HBGF6; HST2; HST2 Oncogene; Heparin Secretory-Transforming Protein 2; Heparin-Binding Growth Factor 6
-90035.jpg)
Fibroblast growth factor 6 is a protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells.
The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.Marics et al. (1989) showed that the cloned normal FGF6 gene transformed mouse NIH 3T3 fibroblasts using both focus and tumorigenicity assays.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA035Hu01 | Recombinant Fibroblast Growth Factor 6 (FGF6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA035Hu01 | Active Fibroblast Growth Factor 6 (FGF6) | Cell culture; Activity Assays. | |
| Antibodies | PAA035Hu01 | Polyclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. |
| MAA035Hu22 | Monoclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. | |
| LAA035Hu81 | FITC-Linked Polyclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IF. | |
| LAA035Hu71 | Biotin-Linked Polyclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC. | |
| Assay Kits | SEA035Hu | ELISA Kit for Fibroblast Growth Factor 6 (FGF6) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA035Hu | CLIA Kit for Fibroblast Growth Factor 6 (FGF6) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA035Mu01 | Recombinant Fibroblast Growth Factor 6 (FGF6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA035Mu02 | Recombinant Fibroblast Growth Factor 6 (FGF6) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA035Mu01 | Polyclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. |
| PAA035Mu02 | Polyclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA035Mu | ELISA Kit for Fibroblast Growth Factor 6 (FGF6) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA035Mu | CLIA Kit for Fibroblast Growth Factor 6 (FGF6) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA035Ra01 | Recombinant Fibroblast Growth Factor 6 (FGF6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA035Ra01 | Polyclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. |
| MAA035Ra21 | Monoclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA035Ra | ELISA Kit for Fibroblast Growth Factor 6 (FGF6) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA035Ra | CLIA Kit for Fibroblast Growth Factor 6 (FGF6) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Danio rerio (Zebrafish)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA035Fi01 | Recombinant Fibroblast Growth Factor 6 (FGF6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA035Fi01 | Polyclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. |
| MAA035Fi21 | Monoclonal Antibody to Fibroblast Growth Factor 6 (FGF6) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA035Fi | ELISA Kit for Fibroblast Growth Factor 6 (FGF6) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA035Fi | CLIA Kit for Fibroblast Growth Factor 6 (FGF6) | Chemiluminescent immunoassay for Antigen Detection. |
- "Putative structure of the FGF6 gene product and role of the signal peptide."Oncogene 6:1437-1444(1991) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Human hst-2 (FGF-6) oncogene: cDNA cloning and characterization."Oncogene 7:303-309(1992) [PubMed] [Europe PMC] [Abstract]
- "Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family."Oncogene 4:335-340(1989) [PubMed] [Europe PMC] [Abstract]
- "Receptor specificity of the fibroblast growth factor family."J. Biol. Chem. 271:15292-15297(1996) [PubMed] [Europe PMC] [Abstract]
- "Fibroblast growth factor signalling: from development to cancer."Nat. Rev. Cancer 10:116-129(2010) [PubMed] [Europe PMC] [Abstract]