Insulin Like Growth Factor 2 (IGF2)

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INSIGF; IGF-II; Somatomedin A; Preptin; Insulin-like growth factor II Ala-25 Del

Insulin Like Growth Factor 2 (IGF2)

IGF2 is a regulatory peptide (IGF-II) critical for normal fetal growth. It has been shown to be implicated in tumor progression in a variety of human neoplasms, eg, Wilms' tumors and rhabdomyosarcomas.

IGF2 transcription is controlled by four distinct promoters, P1 to P4, of which promoters P2, P3, and P4 are epigenetically regulated by genomic imprinting. The IGF-II protein can bind to different receptors: the IGF-I receptor (IGF-IR) has classically been regarded as the major mediator of its proliferative effect; the insulin receptor (IR), especially its isoform A (IR-A), which resembles the IGF-IR in its effect; and the IGF-II receptor (IGF-IIR), which internalizes IGF-II into the cell, thereby regulating its extracellular concentration, and eventually leading to its lysosomal degradation.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Hu01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Hu01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
MAA051Hu22Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
LAA051Hu71Biotin-Linked Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)IHC;WB;ELISA
LAA051Hu81FITC-Linked Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)IHC;ICC;IF;WB
Assay KitsSEA051HuELISA Kit for Insulin Like Growth Factor 2 (IGF2)Enzyme-linked immunosorbent assay
SCA051HuCLIA Kit for Insulin Like Growth Factor 2 (IGF2)Chemiluminescent immunoassay

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Mu01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
RPA051Mu02Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Mu01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
LAA051Mu71Biotin-Linked Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)IHC;WB;ELISA
LAA051Mu81FITC-Linked Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)IHC;ICC;IF;WB
PAA051Mu02Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA051MuELISA Kit for Insulin Like Growth Factor 2 (IGF2)Enzyme-linked immunosorbent assay
SCA051MuCLIA Kit for Insulin Like Growth Factor 2 (IGF2)Chemiluminescent immunoassay

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Ra01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Ra01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
LAA051Ra71Biotin-Linked Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)IHC;WB;ELISA
LAA051Ra81FITC-Linked Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)IHC;ICC;IF;WB
MAA051Ra21Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA051RaELISA Kit for Insulin Like Growth Factor 2 (IGF2)Enzyme-linked immunosorbent assay

Organism species: Cavia (Guinea pig )

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Gu01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Gu01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Insulin Like Growth Factor 2 (IGF2)CLIA Kit Customized Service Offer
n/aELISA Kit for Insulin Like Growth Factor 2 (IGF2)ELISA Kit Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Rb01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Rb51Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
MAA051Rb21Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA051RbELISA Kit for Insulin Like Growth Factor 2 (IGF2)Enzyme-linked immunosorbent assay

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Po01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Po01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
MAA051Po21Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA051PoELISA Kit for Insulin Like Growth Factor 2 (IGF2)Enzyme-linked immunosorbent assay

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Bo01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Bo01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
MAA051Bo21Monoclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA051BoELISA Kit for Insulin Like Growth Factor 2 (IGF2)Enzyme-linked immunosorbent assay

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Cp01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Cp01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Insulin Like Growth Factor 2 (IGF2)CLIA Kit Customized Service Offer
n/aELISA Kit for Insulin Like Growth Factor 2 (IGF2)ELISA Kit Customized Service Offer

Organism species: Ovis aries; Ovine (Sheep)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Insulin Like Growth Factor 2 (IGF2)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Insulin Like Growth Factor 2 (IGF2)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Insulin Like Growth Factor 2 (IGF2)CLIA Kit Customized Service Offer
n/aELISA Kit for Insulin Like Growth Factor 2 (IGF2)ELISA Kit Customized Service Offer

Organism species: Equus caballus; Equine (Horse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Eq01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Eq01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Insulin Like Growth Factor 2 (IGF2)CLIA Kit Customized Service Offer
n/aELISA Kit for Insulin Like Growth Factor 2 (IGF2)ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA051Ga01Recombinant Insulin Like Growth Factor 2 (IGF2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA051Ga01Polyclonal Antibody to Insulin Like Growth Factor 2 (IGF2)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Insulin Like Growth Factor 2 (IGF2)CLIA Kit Customized Service Offer
n/aELISA Kit for Insulin Like Growth Factor 2 (IGF2)ELISA Kit Customized Service Offer
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  21. "Positive associations between single nucleotide polymorphisms in the IGF2 gene region and body mass index in adult males."Hum. Mol. Genet. 10:1491-1501(2001) [PubMed] [Europe PMC] [Abstract]
  22. "Detection of bound and free IGF-1 and IGF-2 in human plasma via biomolecular interaction analysis mass spectrometry."FEBS Lett. 536:130-134(2003) [PubMed] [Europe PMC] [Abstract]
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  25. "Preptin, another peptide product of the pancreatic beta-cell, is osteogenic in vitro and in vivo."Am. J. Physiol. 292:E117-E122(2007) [PubMed] [Europe PMC] [Abstract]
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  28. "Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD."Mol. Cell. Proteomics 0:0-0(2011) [PubMed] [Europe PMC] [Abstract]
  29. "LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."J. Proteome Res. 12:573-584(2013) [PubMed] [Europe PMC] [Abstract]
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