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Tumor Necrosis Factor Beta (TNFb)

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LT; LTA; TNF-B; TNFSF1; Tumor Necrosis Factor Ligand Superfamily Member 1; Lymphotoxin Alpha

Tumor Necrosis Factor Beta (TNFb)
CCC A134
HGNC 6709
MGI 104797
PubMed 11310848
RGD 3020
UniProt P01374
Wiki TNFB

TNF-beta is a potent mediator of inflammatory and immune responses.TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha, TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta, which effectively anchors the TNF-beta to the cell surface. TNF-beta is cytotoxic to a wide range of tumor cells. LTA is highly inducible, secreted, and exists as homotrimeric molecule. LTA forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Hu01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
APA134Hu01 Active Tumor Necrosis Factor Beta (TNFb) Cell culture; Activity Assays.
Antibodies PAA134Hu01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
MAA134Hu22 Monoclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
MAA134Hu21 Monoclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
Assay Kits SEA134Hu ELISA Kit for Tumor Necrosis Factor Beta (TNFb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Mu01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
RPA134Mu02 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA134Mu01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
PAA134Mu02 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
LAA134Mu71 Biotin-Linked Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC.
Assay Kits SEA134Mu ELISA Kit for Tumor Necrosis Factor Beta (TNFb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Ra01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
RPA134Ra02 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
APA134Ra02 Active Tumor Necrosis Factor Beta (TNFb) Cell culture; Activity Assays.
Antibodies PAA134Ra01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
MAA134Ra21 Monoclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
PAA134Ra02 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
Assay Kits SEA134Ra ELISA Kit for Tumor Necrosis Factor Beta (TNFb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Rb01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA134Rb51 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
MAA134Rb21 Monoclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
PAA134Rb01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
Assay Kits SEA134Rb ELISA Kit for Tumor Necrosis Factor Beta (TNFb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Si01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA134Si01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Beta (TNFb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Beta (TNFb) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Ca01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA134Ca01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
LAA134Ca71 Biotin-Linked Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Tumor Necrosis Factor Beta (TNFb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Necrosis Factor Beta (TNFb) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Po01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
APA134Po01 Active Tumor Necrosis Factor Beta (TNFb) Cell culture; Activity Assays.
Antibodies PAA134Po01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
MAA134Po21 Monoclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
Assay Kits SEA134Po ELISA Kit for Tumor Necrosis Factor Beta (TNFb) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA134Bo01 Recombinant Tumor Necrosis Factor Beta (TNFb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA134Bo01 Polyclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
MAA134Bo21 Monoclonal Antibody to Tumor Necrosis Factor Beta (TNFb) WB; IHC; ICC; IP.
Assay Kits SEA134Bo ELISA Kit for Tumor Necrosis Factor Beta (TNFb) Enzyme-linked immunosorbent assay for Antigen Detection.
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  16. "Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy."Nat. Genet. 39:517-522(2007) [PubMed] [Europe PMC] [Abstract]