Ribonuclease A (RNase A)

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RNASE1; RNASE; Rnase-A; RNase UpI-1; RIB-1; Ribonuclease,RNase A Family,1(Pancreatic)

Ribonuclease A (RNase A)

Ribonuclease A (RNase A) is an endonuclease that cleaves single-stranded RNA. Bovine pancreatic RNase A is one of the classic model systems of protein science.RNase A is a relatively small protein. It can be characterized as a two-layer α + β protein that is folded in half to resemble a taco, with a deep cleft for binding the RNA substrate. The first layer is composed of three alpha helices (residues 3-13, 24-34 and 50-60) from the N-terminal half of the protein. The second layer consist of three β-hairpins (residues 61-74, 79-104 and 105-124 from the C-terminal half) arranged in two β-sheets. The hairpins 61-74 and 105-124 form a four-stranded, antiparallel β-sheet that lies on helix 3 (residues 50-60). The longest β-hairpin 79-104 mates with a short β-strand (residues 42-45) to form a three-stranded, antiparallel β-sheet that lies on helix 2 .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA297Hu01 Recombinant Ribonuclease A (RNase A) Positive Control; Immunogen; SDS-PAGE; WB.
APA297Hu01 Active Ribonuclease A (RNase A) Cell culture; Activity Assays.
Antibodies PAA297Hu01 Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IP.
MAA297Hu22 Monoclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IP.
LAA297Hu71 Biotin-Linked Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC.
Assay Kits SEA297Hu ELISA Kit for Ribonuclease A (RNase A) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA297Mu01 Recombinant Ribonuclease A (RNase A) Positive Control; Immunogen; SDS-PAGE; WB.
APA297Mu61 Active Ribonuclease A (RNase A) Cell culture; Activity Assays.
Antibodies PAA297Mu01 Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IP.
LAA297Mu81 FITC-Linked Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IF.
LAA297Mu71 Biotin-Linked Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC.
Assay Kits SEA297Mu ELISA Kit for Ribonuclease A (RNase A) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA297Ra01 Recombinant Ribonuclease A (RNase A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA297Ra01 Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IP.
LAA297Ra81 FITC-Linked Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IF.
LAA297Ra71 Biotin-Linked Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Ribonuclease A (RNase A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribonuclease A (RNase A) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA297Bo01 Recombinant Ribonuclease A (RNase A) Positive Control; Immunogen; SDS-PAGE; WB.
RPA297Bo02 Recombinant Ribonuclease A (RNase A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA297Bo01 Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IP.
LAA297Bo71 Biotin-Linked Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC.
MAA297Bo21 Monoclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IP.
PAA297Bo02 Polyclonal Antibody to Ribonuclease A (RNase A) WB; IHC; ICC; IP.
Assay Kits SEA297Bo ELISA Kit for Ribonuclease A (RNase A) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA297Bo CLIA Kit for Ribonuclease A (RNase A) Chemiluminescent immunoassay for Antigen Detection.
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  18. "'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines."Protein Sci. 16:1389-1397(2007) [PubMed] [Europe PMC] [Abstract]