Lymphotoxin Beta Receptor (LTbR)

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TNFCR; TNFR-RP; TNFR-III; TNFR2-RP; TNFRSF3; Tumor Necrosis Factor Superfamily Member 3; Tumor necrosis factor C receptor; Tumor necrosis factor receptor type III

Lymphotoxin Beta Receptor (LTbR)

LTBR is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of the encoded protein can trigger apoptosis.Not only does the LTBR help trigger apoptosis, it can lead to the release of the cytokine interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. LTBR is also essential for development and organization of the secondary lymphoid organs and chemokine release.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA481Hu01 Recombinant Lymphotoxin Beta Receptor (LTbR) Positive Control; Immunogen; SDS-PAGE; WB.
RPA481Hu02 Recombinant Lymphotoxin Beta Receptor (LTbR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA481Hu01 Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) WB; ICC; IHC-P; IHC-F; ELISA.
LAA481Hu71 Biotin-Linked Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) WB; IHC; ICC.
MAA481Hu21 Monoclonal Antibody to Lymphotoxin Beta Receptor (LTbR) WB; IHC; ICC; IP.
Assay Kits SEA481Hu ELISA Kit for Lymphotoxin Beta Receptor (LTbR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA481Mu01 Recombinant Lymphotoxin Beta Receptor (LTbR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA481Mu01 Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Lymphotoxin Beta Receptor (LTbR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphotoxin Beta Receptor (LTbR) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Lymphotoxin Beta Receptor (LTbR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Lymphotoxin Beta Receptor (LTbR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Lymphotoxin Beta Receptor (LTbR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Lymphotoxin Beta Receptor (LTbR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Lymphotoxin Beta Receptor (LTbR) ELISA Kit Customized Service Offer
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