Protein Kinase D2 (PKD2)

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PRKD2; PRK-D2; PRKD-2; PK-D2; HSPC187; nPKC-D2; Serine/threonine-protein kinase D2

Protein Kinase D2 (PKD2)

Serine/threonine-protein kinase D2 is  encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.

The addition of phosphatidyl-L-serine caused synergistic stimulation. Phorbol ester-activated PRKD2 migrated more slowly than inactive PRKD2 by SDS-PAGE, suggesting hyperphosphorylation upon activation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA510Hu01 Recombinant Protein Kinase D2 (PKD2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA510Hu01 Polyclonal Antibody to Protein Kinase D2 (PKD2) WB; ICC; IHC-P; IHC-F; ELISA.
Assay Kits SEA510Hu ELISA Kit for Protein Kinase D2 (PKD2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA510Mu01 Recombinant Protein Kinase D2 (PKD2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA510Mu01 Polyclonal Antibody to Protein Kinase D2 (PKD2) WB; IHC; ICC; IP.
Assay Kits SEA510Mu ELISA Kit for Protein Kinase D2 (PKD2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Kinase D2 (PKD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Kinase D2 (PKD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Kinase D2 (PKD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Kinase D2 (PKD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Kinase D2 (PKD2) ELISA Kit Customized Service Offer
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  27. "Solution structure of the PH domain of protein kinase C, D2 type from human."Submitted (NOV-2005) to the PDB data bank
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