Leucine Aminopeptidase (LAP)

[Edit]

LAPEP, LAP3; PEPS; Peptidase S; Leucyl Aminopeptidase; Cytosol aminopeptidase; Proline aminopeptidase; Prolyl aminopeptidase

Leucine Aminopeptidase (LAP)

Leucine aminopeptidase (LAP) is an exopeptidase hydrolyzing the peptide bond adjacent to a free amino group. LAP is extensively used in the sequence analysis of proteins and peptides. .The enzyme liberates amino acids from the N-terminal end of a number of proteins and polypeptides. It is called leucine aminopeptidase because it reacts most rapidly with leucine compounds. Many aliphatic amides are also hydrolyzed as well as thiolesters.LAP consists of four subunits each having one atom of zinc.

PEPS levels did not differ from controls in any. This experience permitted exclusion mapping of PEPS to 4p11-4q13; combined with previously reported data, the assignment becomes 4p11-4q12.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA536Hu01Recombinant Leucine Aminopeptidase (LAP)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA536Hu01Polyclonal Antibody to Leucine Aminopeptidase (LAP)WB, ICC, IHC-P, IHC-F, ELISA
MAA536Hu22Monoclonal Antibody to Leucine Aminopeptidase (LAP)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA536HuELISA Kit for Leucine Aminopeptidase (LAP)Enzyme-linked immunosorbent assay

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Leucine Aminopeptidase (LAP)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Leucine Aminopeptidase (LAP)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Leucine Aminopeptidase (LAP)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Leucine Aminopeptidase (LAP)CLIA Kit Customized Service Offer
n/aELISA Kit for Leucine Aminopeptidase (LAP)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA536Ra01Recombinant Leucine Aminopeptidase (LAP)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA536Ra01Polyclonal Antibody to Leucine Aminopeptidase (LAP)WB, ICC, IHC-P, IHC-F, ELISA
MAA536Ra21Monoclonal Antibody to Leucine Aminopeptidase (LAP)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA536RaELISA Kit for Leucine Aminopeptidase (LAP)Enzyme-linked immunosorbent assay
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Structural and immunological evidence for the identity of prolyl aminopeptidase with leucyl aminopeptidase."Biochem. Biophys. Res. Commun. 178:1459-1464(1991) [PubMed] [Europe PMC] [Abstract]
  4. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]