Fatty Acid Binding Protein 2, Intestinal (FABP2)

[Edit]

FABPI; IFABP; I-FABP; Intestinal-type fatty acid-binding protein

Fatty Acid Binding Protein 2, Intestinal (FABP2)

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation.

Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA559Hu01 Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
EPA559Hu61 Eukaryotic Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA559Hu01 Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
MAA559Hu22 Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
Assay Kits SEA559Hu ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA559Hu High Sensitive ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA559Mu01 Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA559Mu02 Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
EPA559Mu61 Eukaryotic Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA559Mu01 Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
LAA559Mu71 Biotin-Linked Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC.
LAA559Mu81 FITC-Linked Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IF.
PAA559Mu02 Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
Assay Kits SEA559Mu ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA559Mu CLIA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA559Ra01 Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA559Ra01 Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
MAA559Ra22 Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB
LAA559Ra71 Biotin-Linked Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC.
LAA559Ra81 FITC-Linked Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IF.
MAA559Ra21 Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
MAA559Ra23 Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB,IHC
MAA559Ra24 Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
Assay Kits SEA559Ra ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA559Po01 Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA559Po01 Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
Assay Kits SEA559Po ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA559Bo01 Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA559Bo01 Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA559Ga01 Recombinant Fatty Acid Binding Protein 2, Intestinal (FABP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Fatty Acid Binding Protein 2, Intestinal (FABP2) Polyclonal Antibody Customized Service Offer
Assay Kits SEA559Ga ELISA Kit for Fatty Acid Binding Protein 2, Intestinal (FABP2) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships."J. Biol. Chem. 262:16060-16071(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility."Clin. Biochem. 36:529-535(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Epidermal growth factor regulates fatty acid uptake and metabolism in Caco-2 cells."Am. J. Physiol. 276:G606-G612(1999) [PubMed] [Europe PMC] [Abstract]
  6. "Consequences of single-site mutations in the intestinal fatty acid binding protein."Biochemistry 42:12192-12199(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit."J. Biomol. NMR 9:213-228(1997) [PubMed] [Europe PMC] [Abstract]
  8. "Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism."Biochemistry 42:7339-7347(2003) [PubMed] [Europe PMC] [Abstract]
  9. "An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance."J. Clin. Invest. 95:1281-1287(1995) [PubMed] [Europe PMC] [Abstract]
  10. "The association of Ala54Thr variant of intestinal fatty acid binding protein gene with general and regional adipose tissue depots."Chin. Med. Sci. J. 14:46-51(1999) [PubMed] [Europe PMC] [Abstract]