P-Selectin (SELP)

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CD62P; Selectin, Platelet; PSEL; GMP140; LECAM3; GRMP; GMRP; PADGEM; Leukocyte-endothelial cell adhesion molecule 3; Platelet activation dependent granule-external membrane

P-Selectin (SELP)

P-selectin is the largest of the known selectins at 140kDa. It contains nine consensus repeats (CR) and extends approximately 40 nm from the endothelial surface. P-selectin is expressed in a-granules of activated platelets and granules of endothelial cells. Within minutes of stimulation of the endothelial cells by inflammatory mediators such as histamine, thrombin, or phorbol esters, P-selectin is surface-expressed. Expression of P-selectin also occurs from the surgical trauma endured during preparation of the tissues for intravital microscopy. The expression is short-lived, reaching its peak after only ten minutes. Additional synthesis of P-selectin is brought about within two hours by cytokines such as interleukin-1 (IL-1) or tumor necrosis factor a (TNF-a).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA569Hu01 Recombinant P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA569Hu02 Recombinant P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
EPA569Hu61 Eukaryotic P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
APA569Hu61 Active P-Selectin (SELP) Cell culture; Activity Assays.
Antibodies PAA569Hu01 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
MAA569Hu22 Monoclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
LAA569Hu71 Biotin-Linked Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC.
LAA569Hu81 FITC-Linked Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IF.
MAA569Hu21 Monoclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
PAA569Hu02 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
MAA569Hu23 Monoclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
MAA569Hu24 Monoclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
Assay Kits SEA569Hu ELISA Kit for P-Selectin (SELP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA569Hu CLIA Kit for P-Selectin (SELP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA569Mu01 Recombinant P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
RPA569Mu02 Recombinant P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA569Mu01 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
LAA569Mu71 Biotin-Linked Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC.
LAA569Mu81 FITC-Linked Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IF.
PAA569Mu02 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
Assay Kits SEA569Mu ELISA Kit for P-Selectin (SELP) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA569Mu CLIA Kit for P-Selectin (SELP) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA569Ra01 Recombinant P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA569Ra01 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
LAA569Ra71 Biotin-Linked Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC.
MAA569Ra21 Monoclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
Assay Kits SEA569Ra ELISA Kit for P-Selectin (SELP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA569Rb01 Recombinant P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA569Rb51 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
MAA569Rb21 Monoclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
PAA569Rb01 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
Assay Kits SEA569Rb ELISA Kit for P-Selectin (SELP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA569Po01 Recombinant P-Selectin (SELP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA569Po01 Polyclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
MAA569Po21 Monoclonal Antibody to P-Selectin (SELP) WB; IHC; ICC; IP.
Assay Kits SEA569Po ELISA Kit for P-Selectin (SELP) Enzyme-linked immunosorbent assay for Antigen Detection.
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  14. ErratumCell 105:971-971(2001)
  15. "The P-selectin gene is highly polymorphic: reduced frequency of the Pro715 allele carriers in patients with myocardial infarction."Hum. Mol. Genet. 7:1277-1284(1998) [PubMed] [Europe PMC] [Abstract]
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  17. ErratumNat. Genet. 23:373-373(1999)
  18. "Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: a population-based, prospective genetic analysis."Hum. Mol. Genet. 13:389-396(2004) [PubMed] [Europe PMC] [Abstract]