Visfatin (VF)

[Edit]

Nampt; NAmPRTase; PBEF; PBEF1; Pre-B-Cell Colony Enhancing Factor; Nicotinamide Phosphoribosyltransferase

Visfatin (VF)

Visfatin, an adipocytokine that is highly enriched in the visceral fat of both Mouses and mice and whose expression level in plasma increases during the development of obesity. Visfatin corresponds to pre-B cell colony-enhancing factor (PBEF), a 52-kD cytokine expressed in lymphocytes. The gene encoding PBEF was originally isolated from an activated lymphocyte cDNA library.The 3-prime UTR of PBEF contains several TATT motifs, destabilizing sequences characteristic of cytokine messages. The deduced 473-amino acid protein has a calculated molecular mass of 52 kDa. PBEF has a hydrophobic N terminus, 2 N-glycosylation sites, several putative phosphorylation sites, and 6 cysteines. Northern blot analysis detected transcripts of about 2.0, 2.4, and 4.0 kb in all tissues examined, with highest expression in liver, followed by muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA638Hu01 Recombinant Visfatin (VF) Positive Control; Immunogen; SDS-PAGE; WB.
CPA638Hu21 OVA Conjugated Visfatin (VF) Immunogen; SDS-PAGE; WB.
Antibodies PAA638Hu01 Polyclonal Antibody to Visfatin (VF) WB; IHC
MAA638Hu22 Monoclonal Antibody to Visfatin (VF) WB
PAA638Hu08 Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
MAA638Hu21 Monoclonal Antibody to Visfatin (VF) WB
MAA638Hu23 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
MAA638Hu24 Monoclonal Antibody to Visfatin (VF) WB; IHC
MAA638Hu25 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
MAA638Hu27 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
MAA638Hu29 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
MAA638Hu26 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
Assay Kits SEA638Hu ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA638Hu ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA638Mu01 Recombinant Visfatin (VF) Positive Control; Immunogen; SDS-PAGE; WB.
RPA638Mu02 Recombinant Visfatin (VF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA638Mu01 Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
PAA638Mu02 Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
Assay Kits SEA638Mu ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA638Mu ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA638Ra01 Recombinant Visfatin (VF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA638Ra01 Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
LAA638Ra71 Biotin-Linked Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC.
LAA638Ra81 FITC-Linked Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC; IF.
MAA638Ra21 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
Assay Kits SEA638Ra ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.
CEA638Ra ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Cavia (Guinea pig )

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA638Gu01 Recombinant Visfatin (VF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA638Gu01 Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
MAA638Gu21 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
Assay Kits SEA638Gu ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA638Po01 Recombinant Visfatin (VF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Visfatin (VF) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Visfatin (VF) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Visfatin (VF) CLIA Kit Customized Service Offer
n/a ELISA Kit for Visfatin (VF) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA638Bo01 Recombinant Visfatin (VF) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA638Bo01 Polyclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
MAA638Bo21 Monoclonal Antibody to Visfatin (VF) WB; IHC; ICC; IP.
Assay Kits SEA638Bo ELISA Kit for Visfatin (VF) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor."Mol. Cell. Biol. 14:1431-1437(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology."Annu. Rev. Nutr. 32:229-243(2012) [PubMed] [Europe PMC] [Abstract]
  9. "Visfatin is secreted into the breast milk and is correlated with weight changes of the infant after the birth."Diabetes Res. Clin. Pract. 96:355-361(2012) [PubMed] [Europe PMC] [Abstract]
  10. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  11. "Visfatin as a novel mediator released by inflamed human endothelial cells."PLoS ONE 8:E78283-E78283(2013) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents."Nat. Struct. Mol. Biol. 13:582-588(2006) [PubMed] [Europe PMC] [Abstract]
  14. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]