Cyclooxygenase-2 (COX 2)

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PGG/HS; PGHS2; PHS2; HCox2; PTGS2; Prostaglandin Endoperoxide Synthase 2; Prostaglandin G/H Synthase And Cyclooxygenase; Prostaglandin H2 synthase 2

Cyclooxygenase-2 (COX 2)

Cyclooxygenase (COX) enzymes catalyze the synthesis of prostaglandins (PGs) from arachidonic acid. There are two isoforms of COX, COX-1 and COX-2. While COX-1 is expressed constitutively and appears to be responsible for the production of prostaglandins (PGs) that control normal physiologic functions, expression of COX-2 is induced by various inflammatory and mitogenic stimuli such as cytokines, growth factors or tumor promoters. Numerous experimental studies suggest a relationship between COX-2 expression and carcinogenesis. For example, increased amounts of COX-2 have been observed in breast cancers that overexpress HER-2/neu. Furthermore, treatment with selective inhibitors of COX-2 reduced the formation of tongue, esophagal, intestinal, breast, skin, lung, and bladder tumors in experimental animals.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA699Hu01 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA699Hu02 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA699Hu03 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA699Hu01 Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB,IHC
MAA699Hu22 Monoclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
PAA699Hu02 Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
Assay Kits SEA699Hu ELISA Kit for Cyclooxygenase-2 (COX 2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA699Mu01 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA699Mu02 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA699Mu01 Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
LAA699Mu71 Biotin-Linked Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC.
LAA699Mu81 FITC-Linked Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IF.
PAA699Mu02 Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
Assay Kits SEA699Mu ELISA Kit for Cyclooxygenase-2 (COX 2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA699Ra01 Recombinant Cyclooxygenase-2 (COX 2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA699Ra01 Polyclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
MAA699Ra21 Monoclonal Antibody to Cyclooxygenase-2 (COX 2) WB; IHC; ICC; IP.
Assay Kits SEA699Ra ELISA Kit for Cyclooxygenase-2 (COX 2) Enzyme-linked immunosorbent assay for Antigen Detection.
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