Cholesteryl Ester Transfer Protein (CETP)

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LTP; Lipid Transfer Protein; Plasma Lipid Transfer Protein; Cholesterylester Transfer Protein

Cholesteryl Ester Transfer Protein (CETP)

Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Most of the time, however, CETP does a homoexchange, trading a triglyceride for a triglyceride or a cholesteryl ester for a cholesteryl ester.

Rare mutations leading to increased function of CETP have been linked to accelerated atherosclerosis. In contrast, a polymorphism (I405V) of the CETP gene leading to lower serum levels has also been linked to exceptional longevity

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA814Hu01Recombinant Cholesteryl Ester Transfer Protein (CETP)SDS-PAGE; WB; ELISA; IP.
RPA814Hu02Recombinant Cholesteryl Ester Transfer Protein (CETP)SDS-PAGE; WB; ELISA; IP.
RPA814Hu03Recombinant Cholesteryl Ester Transfer Protein (CETP)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA814Hu01Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)WB, ICC, IHC-P, IHC-F, ELISA
MAA814Hu22Monoclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)WB, ICC, IHC-P, IHC-F, ELISA
PAA814Hu02Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)WB, ICC, IHC-P, IHC-F, ELISA
PAA814Hu03Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)WB, ICC, IHC-P, IHC-F, ELISA
LAA814Hu71Biotin-Linked Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)IHC;WB;ELISA
Assay KitsSEA814HuELISA Kit for Cholesteryl Ester Transfer Protein (CETP)Enzyme-linked immunosorbent assay

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA814Rb01Recombinant Cholesteryl Ester Transfer Protein (CETP)SDS-PAGE; WB; ELISA; IP.
RPA814Rb02Recombinant Cholesteryl Ester Transfer Protein (CETP)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA814Rb52Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)WB, ICC, IHC-P, IHC-F, ELISA
PAA814Rb51Polyclonal Antibody to Cholesteryl Ester Transfer Protein (CETP)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA814RbELISA Kit for Cholesteryl Ester Transfer Protein (CETP)Enzyme-linked immunosorbent assay
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  11. "A missense mutation in the cholesteryl ester transfer protein gene with possible dominant effects on plasma high density lipoproteins."J. Clin. Invest. 92:2060-2064(1993) [PubMed] [Europe PMC] [Abstract]
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  13. ErratumNat. Genet. 23:373-373(1999)
  14. "Two novel missense mutations in the CETP gene in Japanese hyperalphalipoproteinemic subjects: high-throughput assay by Invader assay."J. Lipid Res. 43:1011-1018(2002) [PubMed] [Europe PMC] [Abstract]
  15. "Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors."Hum. Mol. Genet. 12:2733-2743(2003) [PubMed] [Europe PMC] [Abstract]