Nitric Oxide Synthase 1, Neuronal (NOS1)

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NOS; nNOS; IHPS1; NC-NOS; N-NOS; bNOS; Neuronal NOS; Constitutive NOS; NOS type I; Nitric Ocide Synthase; Peptidyl-cysteine S-nitrosylase NOS1

Nitric Oxide Synthase 1, Neuronal (NOS1)

Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter; it is implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. NO is also responsible for endothelium-derived relaxing factor activity regulating blood pressure. NO mediates tumoricidal and bactericidal actions, as indicated by the fact that inhibitors of NO synthase (NOS) block these effects. Neuronal NOS and macrophage NOS are distinct isoforms.Both the neuronal and the macrophage forms are unusual among oxidative enzymes in requiring several electron donors: FAD, flavin mononucleotide (FMN), NADPH, and tetrahydrobiopterin.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA815Hu01Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA815Hu01Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
MAA815Hu22Monoclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
LAA815Hu71Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB; ICC; IHC-P; IHC-F; IF; ELISA.
Assay KitsSEA815HuELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1)Enzyme-linked immunosorbent assay for Antigen Detection
SCA815HuCLIA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1)Chemiluminescent immunoassay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA815Mu02Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP.
RPA815Mu03Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP; CoIP; Reporter Assays; Purification; Amine Reactive Labeling.
RPA815Mu01Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP.
RPA815Mu04Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA815Mu01Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
PAA815Mu02Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
PAA815Mu03Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
PAA815Mu04Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
LAA815Mu71Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)IHC;WB;ELISA
Assay Kitsn/aCLIA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1)CLIA Kit Customized Service Offer
n/aELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA815Ra01Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP.
RPA815Ra02Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP.
RPA815Ra03Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA815Ra01Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
PAA815Ra02Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
LAA815Ra71Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)IHC;WB;ELISA
PAA815Ra03Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA815RaELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Nitric Oxide Synthase 1, Neuronal (NOS1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1)CLIA Kit Customized Service Offer
n/aELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1)ELISA Kit Customized Service Offer
  1. "Structural organization of the human neuronal nitric oxide synthase gene (NOS1)."J. Biol. Chem. 269:33082-33090(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines."J. Neurochem. 63:140-145(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle."FEBS Lett. 316:175-180(1993) [PubMed] [Europe PMC] [Abstract]
  4. "Neuronal isoform of nitric oxide synthase is expressed at low levels in human retina."Cell. Mol. Neurobiol. 16:499-515(1996) [PubMed] [Europe PMC] [Abstract]
  5. "A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase."J. Biol. Chem. 272:11392-11401(1997) [PubMed] [Europe PMC] [Abstract]
  6. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Isolation and characterization of a novel, human neuronal nitric oxide synthase cDNA."Biochem. Biophys. Res. Commun. 251:898-902(1998) [PubMed] [Europe PMC] [Abstract]