Nitric Oxide Synthase 1, Neuronal (NOS1)

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NOS; nNOS; IHPS1; NC-NOS; N-NOS; bNOS; Neuronal NOS; Constitutive NOS; NOS type I; Nitric Ocide Synthase; Peptidyl-cysteine S-nitrosylase NOS1

Nitric Oxide Synthase 1, Neuronal (NOS1)

Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter; it is implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. NO is also responsible for endothelium-derived relaxing factor activity regulating blood pressure. NO mediates tumoricidal and bactericidal actions, as indicated by the fact that inhibitors of NO synthase (NOS) block these effects. Neuronal NOS and macrophage NOS are distinct isoforms.Both the neuronal and the macrophage forms are unusual among oxidative enzymes in requiring several electron donors: FAD, flavin mononucleotide (FMN), NADPH, and tetrahydrobiopterin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA815Hu01 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA815Hu01 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
MAA815Hu22 Monoclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
LAA815Hu71 Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC.
Assay Kits SEA815Hu ELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA815Hu CLIA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA815Mu02 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA815Mu03 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA815Mu01 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA815Mu04 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA815Mu01 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
PAA815Mu02 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
PAA815Mu03 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
PAA815Mu04 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
LAA815Mu71 Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA815Ra01 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA815Ra02 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA815Ra03 Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA815Ra01 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
PAA815Ra02 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
LAA815Ra71 Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC.
PAA815Ra03 Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) WB; IHC; ICC; IP.
Assay Kits SEA815Ra ELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nitric Oxide Synthase 1, Neuronal (NOS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nitric Oxide Synthase 1, Neuronal (NOS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nitric Oxide Synthase 1, Neuronal (NOS1) ELISA Kit Customized Service Offer
  1. "Structural organization of the human neuronal nitric oxide synthase gene (NOS1)."J. Biol. Chem. 269:33082-33090(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines."J. Neurochem. 63:140-145(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle."FEBS Lett. 316:175-180(1993) [PubMed] [Europe PMC] [Abstract]
  4. "Neuronal isoform of nitric oxide synthase is expressed at low levels in human retina."Cell. Mol. Neurobiol. 16:499-515(1996) [PubMed] [Europe PMC] [Abstract]
  5. "A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase."J. Biol. Chem. 272:11392-11401(1997) [PubMed] [Europe PMC] [Abstract]
  6. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Isolation and characterization of a novel, human neuronal nitric oxide synthase cDNA."Biochem. Biophys. Res. Commun. 251:898-902(1998) [PubMed] [Europe PMC] [Abstract]