Prolactin (PRL)

Luteotropic hormone is a peptide hormone discovered by Dr. Henry Friesen, primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of prolactin, which fills the breast with milk via a process called lactogenesis, in preparation for the next feed. Oxytocin, another hormone, is also released, which triggers milk let-down.Prolactin (PRL) is a peptide hormone primarily associated with lactation. In breastfeeding, the infant suckling the teat stimulates the production of prolactin, which fills the breast with milk (lactogenesis) in preparation for the next feed. Oxytocin, a similar hormone, is also released, which triggers milk let-down. Prolactin (PRL) is a polypeptide hormone secreted by anterior pituitary of both male and female.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA846Hu01Recombinant Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
EPA846Hu61Eukaryotic Prolactin (PRL)SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling.
AntibodiesPAA846Hu01Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
MAA846Hu22Monoclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
LAA846Hu71Biotin-Linked Polyclonal Antibody to Prolactin (PRL)IHC;WB;ELISA
PAA846Hu06Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA846HuELISA Kit for Prolactin (PRL)Enzyme-linked immunosorbent assay for Antigen Detection
SCA846HuCLIA Kit for Prolactin (PRL)Chemiluminescent immunoassay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA846Mu01Recombinant Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
RPA846Mu02Recombinant Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
APA846Mu01Active Prolactin (PRL)Cell culture; Activity Assays; In vivo assays.
AntibodiesPAA846Mu01Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
PAA846Mu02Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA846MuELISA Kit for Prolactin (PRL)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA846Ra01Recombinant Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
CPA846Ra21OVA Conjugated Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA846Ra01Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
MAA846Ra21Monoclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
PAA846Ra08Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA846RaELISA Kit for Prolactin (PRL)Enzyme-linked immunosorbent assay for Antigen Detection
CEA846RaELISA Kit for Prolactin (PRL)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA846Rb01Recombinant Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA846Rb51Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
MAA846Rb21Monoclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsCEA846RbELISA Kit for Prolactin (PRL)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA846Po01Recombinant Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA846Po01Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
MAA846Po21Monoclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA846PoELISA Kit for Prolactin (PRL)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA846Bo01Recombinant Prolactin (PRL)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA846Bo01Polyclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
MAA846Bo21Monoclonal Antibody to Prolactin (PRL)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA846BoELISA Kit for Prolactin (PRL)Enzyme-linked immunosorbent assay for Antigen Detection
  1. "Human prolactin. cDNA structural analysis and evolutionary comparisons."J. Biol. Chem. 256:4007-4016(1981) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation and characterization of the human prolactin gene."EMBO J. 3:429-437(1984) [PubMed] [Europe PMC] [Abstract]
  3. "A placenta-specific 5'non-coding exon of human prolactin."Mol. Cell. Endocrinol. 75:71-80(1991) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Molecular cloning and nucleotide sequence of DNA complementary to human decidual prolactin mRNA."J. Biochem. 95:1491-1499(1984) [PubMed] [Europe PMC] [Abstract]
  6. "Expression of the prolactin gene in normal and neoplastic human breast tissues and human mammary cell lines: promoter usage and alternative mRNA splicing."Breast Cancer Res. Treat. 44:243-253(1997) [PubMed] [Europe PMC] [Abstract]
  7. "Human pituitary prolactin (hPRL): the entire linear amino acid sequence."J. Clin. Endocrinol. Metab. 45:1112-1115(1977) [PubMed] [Europe PMC] [Abstract]
  8. "High sensitivity automated sequence determination of polypeptides."J. Biol. Chem. 250:3629-3636(1975) [PubMed] [Europe PMC] [Abstract]
  9. "Immunoglobulin G subclasses and prolactin (PRL) isoforms in macroprolactinemia due to anti-PRL autoantibodies."J. Clin. Endocrinol. Metab. 90:3036-3044(2005) [PubMed] [Europe PMC] [Abstract]
  10. "The tertiary structure and backbone dynamics of human prolactin."J. Mol. Biol. 328:1105-1121(2003) [PubMed] [Europe PMC] [Abstract]
  11. "Solution structure of human prolactin."J. Mol. Biol. 351:810-823(2005) [PubMed] [Europe PMC] [Abstract]
  12. "Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL."J. Biol. Chem. 282:33118-33131(2007) [PubMed] [Europe PMC] [Abstract]
  13. "Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor."J. Biol. Chem. 283:19085-19094(2008) [PubMed] [Europe PMC] [Abstract]