Phospholipase A2 Group VII (LpPLA2)
[Edit]PLA2G7; PAF-AH; PAFAH; Lp-PLA2; LDL-PLA2; Platelet Activating Factor Acetylhydrolase,Plasma; Phospholipase A2,Group VII; LDL-associated phospholipase A2; Phospholipase A2, Lipoprotein Associated
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Lipoprotein-associated phospholipase A2 (Lp-PLA2, also known as platelet activating factor acetyl-hydrolase), is a relatively recent marker that has emerged as a major, independent predictor of CHD. Lp-PLA2 is an active phospholipase that circulates in plasma bound to LDL, and it appears to act almost exclusively on oxidized LDL to generate lysophosphatidyl-choline, which is proinflammatory and is considered to be atherogenic. Thus, Lp-PLA2 represents an interesting link between lipoproteinoxidation and vascular inflammation, which likely explain its strong, independent association with CHD risk. Data from the recent ARIC study have indicated that the predictive power of Lp-PLA2 is attenuated after adjustment for multiple established risk factors.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA867Ra01 | Recombinant Phospholipase A2 Group VII (LpPLA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA867Ra61 | Eukaryotic Phospholipase A2 Group VII (LpPLA2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APA867Ra61 | Active Phospholipase A2 Group VII (LpPLA2) | Cell culture; Activity Assays. | |
| Antibodies | PAA867Ra01 | Polyclonal Antibody to Phospholipase A2 Group VII (LpPLA2) | WB; IHC; ICC; IP. |
| Assay Kits | SEA867Ra | ELISA Kit for Phospholipase A2 Group VII (LpPLA2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA867Ca01 | Recombinant Phospholipase A2 Group VII (LpPLA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA867Ca01 | Polyclonal Antibody to Phospholipase A2 Group VII (LpPLA2) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Phospholipase A2 Group VII (LpPLA2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Phospholipase A2 Group VII (LpPLA2) | ELISA Kit Customized Service Offer |
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