Gastric Inhibitory Polypeptide (GIP)

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Incretin hormone; Glucose Dependent Insulinotropic Peptide

Gastric Inhibitory Polypeptide (GIP)

Gastric inhibitory polypeptide (GIP), is a member of the secretin family of hormones.GIP is derived from a 153-amino acid proprotein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide. It is synthesized by K cells, which are found in the mucosa of the duodenum and the jejunum of the gastrointestinal tract.Like all endocrine hormones, it is transported by blood. It is now believed that the function of GIP is to induce insulin secretion, which is primarily stimulated by hyperosmolarity of glucose in the duodenum. After this discovery, some researchers prefer the new name of glucose-dependent insulinotropic peptide, while retaining the acronym "GIP." The amount of insulin secreted is greater when glucose is administered orally than intravenously.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA882Hu01Recombinant Gastric Inhibitory Polypeptide (GIP)SDS-PAGE; WB; ELISA; IP.
CPA882Hu11BSA Conjugated Gastric Inhibitory Polypeptide (GIP)SDS-PAGE; WB; ELISA; IP.
CPA882Hu21OVA Conjugated Gastric Inhibitory Polypeptide (GIP)Immunogen; Coating Antigen; Blocking Peptide; ELISA.
AntibodiesPAA882Hu01Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
MAA882Hu22Monoclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
MAA882Hu21Monoclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
PAA882Hu08Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsCEA882HuELISA Kit for Gastric Inhibitory Polypeptide (GIP)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA882Mu01Recombinant Gastric Inhibitory Polypeptide (GIP)SDS-PAGE; WB; ELISA; IP.
RPA882Mu02Recombinant Gastric Inhibitory Polypeptide (GIP)SDS-PAGE; WB; ELISA; IP.
CPA882Mu11BSA Conjugated Gastric Inhibitory Polypeptide (GIP)Immunogen; Coating Antigen; Blocking Peptide; ELISA.
CPA882Mu21OVA Conjugated Gastric Inhibitory Polypeptide (GIP)Immunogen; Coating Antigen; Blocking Peptide; ELISA.
AntibodiesPAA882Mu01Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
PAA882Mu02Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
PAA882Mu08Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsCEA882MuELISA Kit for Gastric Inhibitory Polypeptide (GIP)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA882Ra01Recombinant Gastric Inhibitory Polypeptide (GIP)SDS-PAGE; WB; ELISA; IP.
CPA882Ra11BSA Conjugated Gastric Inhibitory Polypeptide (GIP)Immunogen; Coating Antigen; Blocking Peptide; ELISA.
CPA882Ra21OVA Conjugated Gastric Inhibitory Polypeptide (GIP)Immunogen; Coating Antigen; Blocking Peptide; ELISA.
AntibodiesPAA882Ra01Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
MAA882Ra21Monoclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
PAA882Ra08Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsCEA882RaELISA Kit for Gastric Inhibitory Polypeptide (GIP)Enzyme-linked immunosorbent assay for Antigen Detection
  1. "Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor."Proc. Natl. Acad. Sci. U.S.A. 84:7005-7008(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Gastric inhibitory polypeptide: structure and chromosomal localization of the human gene."Mol. Endocrinol. 3:1014-1021(1989) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The isolation and sequencing of human gastric inhibitory peptide (GIP)."FEBS Lett. 172:142-148(1984) [PubMed] [Europe PMC] [Abstract]
  5. "NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide."Biochem. Biophys. Res. Commun. 325:281-286(2004) [PubMed] [Europe PMC] [Abstract]