Cystatin 3 (CST3)

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Cys-C; Cystatin C; Gamma Trace; Post-Gamma-Globulin; Neuroendocrine Basic Polypeptide; Amyloid Angiopathy And Cerebral Hemorrhage

Cystatin 3 (CST3)

Cystatin C: A serum protein that is filtered out of the blood by the kidneys and that serves as a measure of kidney function. Cystatin C is produced steadily by all types of nucleated cells in the body. Its low molecular mass allows it to be freely filtered by the glomerular membrane in the kidney.

Its concentration in blood correlates with the glomerular filtration rate. The levels of cystatin C are independent of weight and height, muscle mass, age (over a year of age), and sex. Measurements can be made and interpreted from a single random sample. Cystatin C is a better marker of the glomerular filtration rate and hence of kidney function than creatinine which was the most commonly used measure of kidney function.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA896Hu01Recombinant Cystatin 3 (CST3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA896Hu01Polyclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
MAA896Hu21Monoclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
MAA896Hu22Monoclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
LAA896Hu71Biotin-Linked Polyclonal Antibody to Cystatin 3 (CST3)IHC;WB;ELISA
Assay KitsSEA896HuELISA Kit for Cystatin 3 (CST3)Enzyme-linked immunosorbent assay
SCA896HuCLIA Kit for Cystatin 3 (CST3)Chemiluminescent immunoassay

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA896Mu01Recombinant Cystatin 3 (CST3)SDS-PAGE; WB; ELISA; IP.
RPA896Mu02Recombinant Cystatin 3 (CST3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA896Mu01Polyclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
PAA896Mu02Polyclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA896MuELISA Kit for Cystatin 3 (CST3)Enzyme-linked immunosorbent assay

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA896Ra01Recombinant Cystatin 3 (CST3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA896Ra01Polyclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
MAA896Ra21Monoclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
LAA896Ra71Biotin-Linked Polyclonal Antibody to Cystatin 3 (CST3)IHC;WB;ELISA
Assay KitsSEA896RaELISA Kit for Cystatin 3 (CST3)Enzyme-linked immunosorbent assay

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Cystatin 3 (CST3)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Cystatin 3 (CST3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Cystatin 3 (CST3)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Cystatin 3 (CST3)CLIA Kit Customized Service Offer
n/aELISA Kit for Cystatin 3 (CST3)ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA896Po01Recombinant Cystatin 3 (CST3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA896Po01Polyclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
MAA896Po21Monoclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA896PoELISA Kit for Cystatin 3 (CST3)Enzyme-linked immunosorbent assay

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA896Bo01Recombinant Cystatin 3 (CST3)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA896Bo01Polyclonal Antibody to Cystatin 3 (CST3)WB, ICC, IHC-P, IHC-F, ELISA
LAA896Bo71Biotin-Linked Polyclonal Antibody to Cystatin 3 (CST3)IHC;WB;ELISA
LAA896Bo81FITC-Linked Polyclonal Antibody to Cystatin 3 (CST3)IHC;ICC;IF;WB
Assay Kitsn/aCLIA Kit for Cystatin 3 (CST3)CLIA Kit Customized Service Offer
n/aELISA Kit for Cystatin 3 (CST3)ELISA Kit Customized Service Offer
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  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis."Proc. Natl. Acad. Sci. U.S.A. 79:3024-3027(1982) [PubMed] [Europe PMC] [Abstract]
  9. "Human cystatin, a new protein inhibitor of cysteine proteinases."Biochem. Biophys. Res. Commun. 118:103-109(1984) [PubMed] [Europe PMC] [Abstract]
  10. "Protein inhibitors of cysteine proteinases. III. Amino-acid sequence of cystatin from chicken egg white."Hoppe-Seyler's Z. Physiol. Chem. 364:1487-1496(1983) [PubMed] [Europe PMC] [Abstract]
  11. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  12. "The disulphide bridges of human cystatin C (gamma-trace) and chicken cystatin."FEBS Lett. 170:370-374(1984)
  13. "Cystatin C as a potential cerebrospinal fluid marker for the diagnosis of Creutzfeldt-Jakob disease."Proteomics 4:2229-2233(2004) [PubMed] [Europe PMC] [Abstract]
  14. "A dual Golgi- and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility."Exp. Eye Res. 84:1135-1139(2007) [PubMed] [Europe PMC] [Abstract]
  15. "Enrichment of glycopeptides for glycan structure and attachment site identification."Nat. Methods 6:809-811(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry."J. Am. Soc. Mass Spectrom. 21:908-917(2010) [PubMed] [Europe PMC] [Abstract]
  17. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  18. "Resveratrol-induced changes of the human adipocyte secretion profile."J. Proteome Res. 11:4733-4743(2012) [PubMed] [Europe PMC] [Abstract]
  19. "Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping."Nat. Struct. Biol. 8:316-320(2001) [PubMed] [Europe PMC] [Abstract]
  20. "3D domain-swapped human cystatin C with amyloid-like intermolecular beta-sheets."Proteins 61:570-578(2005) [PubMed] [Europe PMC] [Abstract]
  21. "Hereditary cystatin C amyloid angiopathy: identification of the disease-causing mutation and specific diagnosis by polymerase chain reaction based analysis."Hum. Genet. 89:377-380(1992) [PubMed] [Europe PMC] [Abstract]
  22. "CST3 genotype associated with exudative age related macular degeneration."Br. J. Ophthalmol. 86:214-219(2002) [PubMed] [Europe PMC] [Abstract]