Cluster Of Differentiation 42b (CD42b)

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GP1Ba; CD42-B; CD42b-Alpha; GP1-BA; BSS; GP1B; GPIBA; Glycocalicin; Glycoprotein Ib Alpha Polypeptide, Platelet

Cluster Of Differentiation 42b (CD42b)

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB108Hu01 Recombinant Cluster Of Differentiation 42b (CD42b) Positive Control; Immunogen; SDS-PAGE; WB.
EPB108Hu61 Eukaryotic Cluster Of Differentiation 42b (CD42b) Positive Control; Immunogen; SDS-PAGE; WB.
APB108Hu61 Active Cluster Of Differentiation 42b (CD42b) Cell culture; Activity Assays.
Antibodies PAB108Hu01 Polyclonal Antibody to Cluster Of Differentiation 42b (CD42b) WB; IHC; ICC; IP.
MAB108Hu21 Monoclonal Antibody to Cluster Of Differentiation 42b (CD42b) WB; IHC; ICC; IP.
Assay Kits SEB108Hu ELISA Kit for Cluster Of Differentiation 42b (CD42b) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB108Mu01 Recombinant Cluster Of Differentiation 42b (CD42b) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB108Mu01 Polyclonal Antibody to Cluster Of Differentiation 42b (CD42b) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cluster Of Differentiation 42b (CD42b) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cluster Of Differentiation 42b (CD42b) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cluster Of Differentiation 42b (CD42b) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cluster Of Differentiation 42b (CD42b) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cluster Of Differentiation 42b (CD42b) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cluster Of Differentiation 42b (CD42b) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cluster Of Differentiation 42b (CD42b) ELISA Kit Customized Service Offer
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  30. ErratumNat. Genet. 23:373-373(1999)
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