Chemokine C-C-Motif Ligand 1 (CCL1)

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SCYA1; I-309; TCA3; P500; SISe; Small Inducible Cytokine A1; T Lymphocyte Secreted Protein I-309

Chemokine C-C-Motif Ligand 1 (CCL1)

Chemokine (C-C motif) ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells that belongs to a family inflammatory cytokines known as chemokines. The inflammatory cytokine I-309 is one of the small inducible chemotactic and inflammatory peptides which have a hydrophobic leader sequence typical of secreted proteins; in many cases the products have indeed been demonstrated to be secreted. Comparison of amino acid sequences of the gene products show that they share numerous conserved amino acids, most notably 4 cysteine residues that are arranged in a characteristic motif. The superfamily is divided into 2 subfamilies, which are called CC or CXC, depending on whether the protein has 2 adjacent cysteine residues or has a single amino acid separating the 2 cysteine residues, respectively.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB132Hu01 Recombinant Chemokine C-C-Motif Ligand 1 (CCL1) Positive Control; Immunogen; SDS-PAGE; WB.
APB132Hu01 Active Chemokine C-C-Motif Ligand 1 (CCL1) Cell culture; Activity Assays.
EPB132Hu61 Eukaryotic Chemokine C-C-Motif Ligand 1 (CCL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB132Hu01 Polyclonal Antibody to Chemokine C-C-Motif Ligand 1 (CCL1) WB; IHC; ICC; IP.
MAB132Hu21 Monoclonal Antibody to Chemokine C-C-Motif Ligand 1 (CCL1) WB; IHC; ICC; IP.
Assay Kits SEB132Hu ELISA Kit for Chemokine C-C-Motif Ligand 1 (CCL1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB132Mu01 Recombinant Chemokine C-C-Motif Ligand 1 (CCL1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB132Mu02 Recombinant Chemokine C-C-Motif Ligand 1 (CCL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB132Mu01 Polyclonal Antibody to Chemokine C-C-Motif Ligand 1 (CCL1) WB; IHC; ICC; IP.
PAB132Mu02 Polyclonal Antibody to Chemokine C-C-Motif Ligand 1 (CCL1) WB; IHC; ICC; IP.
Assay Kits SEB132Mu ELISA Kit for Chemokine C-C-Motif Ligand 1 (CCL1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB132Ra01 Recombinant Chemokine C-C-Motif Ligand 1 (CCL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB132Ra01 Polyclonal Antibody to Chemokine C-C-Motif Ligand 1 (CCL1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Chemokine C-C-Motif Ligand 1 (CCL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine C-C-Motif Ligand 1 (CCL1) ELISA Kit Customized Service Offer

Organism species: Hamster (Chinese hamster)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB132Ha01 Recombinant Chemokine C-C-Motif Ligand 1 (CCL1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Chemokine C-C-Motif Ligand 1 (CCL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chemokine C-C-Motif Ligand 1 (CCL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chemokine C-C-Motif Ligand 1 (CCL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine C-C-Motif Ligand 1 (CCL1) ELISA Kit Customized Service Offer
  1. "A novel polypeptide secreted by activated human T lymphocytes."J. Immunol. 143:2907-2916(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines."J. Immunol. 145:2737-2744(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The human cytokine I-309 is a monocyte chemoattractant."Proc. Natl. Acad. Sci. U.S.A. 89:2950-2954(1992) [PubMed] [Europe PMC] [Abstract]
  7. "Human CC chemokine I-309, structural consequences of the additional disulfide bond."Biochemistry 39:6053-6059(2000) [PubMed] [Europe PMC] [Abstract]