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Transferrin Receptor (TFR)

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CD71; TFR1; P90; TFRC; T9; Trfr; sTfR; Transferrin receptor protein 1, serum form

Transferrin Receptor (TFR)
CCC B171
HGNC 11763
MGI 98822
PubMed 12589962
RGD 70488
UniProt P02786
Wiki TFR

Transferrin receptor  is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis. Expression of human TFR1, but not human TFR2, in hamster cell lines markedly enhanced the infection of viruses pseudotyped with the glycoprotein of Machupo, Guanarito, and Junin viruses, but not with those of Lassa or lymphocytic choriomeningitis viruses. An anti-TFR1 antibody efficiently inhibited the replication of Machupo, Guanarito, Junin, and Sabia viruses, but not that of Lassa virus.TFR1 is a cellular receptor for New World hemorrhagic fever arenaviruses.

 

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB171Hu01 Recombinant Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
EPB171Hu61 Eukaryotic Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
EPB171Hu62 Eukaryotic Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
APB171Hu61 Active Transferrin Receptor (TFR) Cell culture; Activity Assays.
APB171Hu62 Active Transferrin Receptor (TFR) Cell culture; Activity Assays.
Antibodies PAB171Hu01 Polyclonal Antibody to Transferrin Receptor (TFR) WB
MAB171Hu22 Monoclonal Antibody to Transferrin Receptor (TFR) IHC
LAB171Hu71 Biotin-Linked Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC.
LAB171Hu81 FITC-Linked Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IF.
CAB171Hu22 Anti-Transferrin Receptor (TFR) Monoclonal Antibody Loading Control of WB.
CAB171Hu01 Anti-Transferrin Receptor (TFR) Polyclonal Antibody Loading Control of WB.
MAB171Hu21 Monoclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
MAB171Hu26 Monoclonal Antibody to Transferrin Receptor (TFR) WB
CAB171Hu24 Anti-Transferrin Receptor (TFR) Monoclonal Antibody Loading Control of WB.
MAB171Hu23 Monoclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
MAB171Hu24 Monoclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
MAB171Hu25 Monoclonal Antibody to Transferrin Receptor (TFR) WB
Assay Kits SEB171Hu ELISA Kit for Transferrin Receptor (TFR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB171Mu01 Recombinant Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
RPB171Mu02 Recombinant Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB171Mu01 Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
LAB171Mu71 Biotin-Linked Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC.
PAB171Mu02 Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
Assay Kits SEB171Mu ELISA Kit for Transferrin Receptor (TFR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB171Ra01 Recombinant Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB171Ra01 Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
MAB171Ra21 Monoclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
Assay Kits SEB171Ra ELISA Kit for Transferrin Receptor (TFR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB171Po01 Recombinant Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
NPB171Po01 Native Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB171Po01 Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
LAB171Po71 Biotin-Linked Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC.
MAB171Po21 Monoclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Transferrin Receptor (TFR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transferrin Receptor (TFR) ELISA Kit Customized Service Offer

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB171Eq01 Recombinant Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB171Eq01 Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Transferrin Receptor (TFR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transferrin Receptor (TFR) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB171Ga01 Recombinant Transferrin Receptor (TFR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB171Ga01 Polyclonal Antibody to Transferrin Receptor (TFR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Transferrin Receptor (TFR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transferrin Receptor (TFR) ELISA Kit Customized Service Offer
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  26. "Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses."Nature 446:92-96(2007) [PubMed] [Europe PMC] [Abstract]
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  28. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
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  30. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
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  32. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
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