-91203.jpg)
Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction with the dopaminergic system. Neurotensin was first isolated from extracts of bovine hypothalamus based on its ability to cause a visible vasodilation in the exposed cutaneous regions of anesthetized rats.The sequence of bovine neurotensin was determined to be pyroGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH. Neurotensin is synthesized as part of a 169-170 amino acid precursor protein that also contains the related neuropeptide neuromedin N. The peptide coding domains are located in tandem near the carboxyl terminal end of the precursor and are bounded and separated by paired basic amino acid (lysine-arginine) processing sites.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB203Hu01 | Recombinant Neurotensin (NT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| SPB203Hu01 | Synthetic Neurotensin (NT) | Immunogen; Blocking Peptide. | |
| CPB203Hu21 | OVA Conjugated Neurotensin (NT) | Immunogen; SDS-PAGE; WB. | |
| CPB203Hu22 | OVA Conjugated Neurotensin (NT) | Immunogen; SDS-PAGE; WB. | |
| RPB203Hu02 | Recombinant Neurotensin (NT) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB203Hu01 | Polyclonal Antibody to Neurotensin (NT) | WB; IHC; ICC; IP. |
| MAB203Hu22 | Monoclonal Antibody to Neurotensin (NT) | WB; IHC; ICC; IP. | |
| PAB203Hu02 | Polyclonal Antibody to Neurotensin (NT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEB203Hu | ELISA Kit for Neurotensin (NT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEB203Hu | High Sensitive ELISA Kit for Neurotensin (NT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB203Mu01 | Recombinant Neurotensin (NT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPB203Mu21 | OVA Conjugated Neurotensin (NT) | Immunogen; SDS-PAGE; WB. | |
| CPB203Mu22 | OVA Conjugated Neurotensin (NT) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB203Mu01 | Polyclonal Antibody to Neurotensin (NT) | WB; IHC; ICC; IP. |
| Assay Kits | CEB203Mu | ELISA Kit for Neurotensin (NT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB203Ra01 | Recombinant Neurotensin (NT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPB203Ra21 | OVA Conjugated Neurotensin (NT) | Immunogen; SDS-PAGE; WB. | |
| CPB203Ra22 | OVA Conjugated Neurotensin (NT) | Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB203Ra01 | Polyclonal Antibody to Neurotensin (NT) | WB; IHC; ICC; IP. |
| MAB203Ra21 | Monoclonal Antibody to Neurotensin (NT) | WB; IHC; ICC; IP. | |
| Assay Kits | CEB203Ra | ELISA Kit for Neurotensin (NT) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "DNA methylation contributes to expression of the human neurotensin/neuromedin N gene."Am. J. Physiol. 274:G535-G543(1998) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Cloning of human neurotensin/neuromedin N genomic sequences and expression in the ventral mesencephalon of schizophrenics and age/sex matched controls."Neuroscience 50:259-268(1992) [PubMed] [Europe PMC] [Abstract]
- "Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain."Nat. Struct. Mol. Biol. 16:96-98(2009) [PubMed] [Europe PMC] [Abstract]
- "Intermolecular interactions between the neurotensin and the third extracellular loop of human neurotensin 1 receptor."J. Biomol. Struct. Dyn. 31:1381-1392(2013) [PubMed] [Europe PMC] [Abstract]