Cluster Of Differentiation 73 (CD73)
[Edit]NT5E; NT5-E; E5NT; E5-NT; NTE; EN; ENT; 5'-Nucleotidase, Ecto
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Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane.
The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases . Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB250Mu01 | Recombinant Cluster Of Differentiation 73 (CD73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB250Mu01 | Polyclonal Antibody to Cluster Of Differentiation 73 (CD73) | WB; IHC; ICC; IP. |
| LAB250Mu71 | Biotin-Linked Polyclonal Antibody to Cluster Of Differentiation 73 (CD73) | WB; IHC; ICC. | |
| LAB250Mu81 | FITC-Linked Polyclonal Antibody to Cluster Of Differentiation 73 (CD73) | WB; IHC; ICC; IF. | |
| Assay Kits | n/a | CLIA Kit for Cluster Of Differentiation 73 (CD73) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Cluster Of Differentiation 73 (CD73) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB250Ra01 | Recombinant Cluster Of Differentiation 73 (CD73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB250Ra01 | Polyclonal Antibody to Cluster Of Differentiation 73 (CD73) | WB; IHC; ICC; IP. |
| LAB250Ra71 | Biotin-Linked Polyclonal Antibody to Cluster Of Differentiation 73 (CD73) | WB; IHC; ICC. | |
| MAB250Ra21 | Monoclonal Antibody to Cluster Of Differentiation 73 (CD73) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB250Ra | ELISA Kit for Cluster Of Differentiation 73 (CD73) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Cluster Of Differentiation 73 (CD73) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Cluster Of Differentiation 73 (CD73) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Cluster Of Differentiation 73 (CD73) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Cluster Of Differentiation 73 (CD73) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Cluster Of Differentiation 73 (CD73) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB250Bo01 | Recombinant Cluster Of Differentiation 73 (CD73) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAB250Bo01 | Polyclonal Antibody to Cluster Of Differentiation 73 (CD73) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Cluster Of Differentiation 73 (CD73) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Cluster Of Differentiation 73 (CD73) | ELISA Kit Customized Service Offer |
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- "NT5E mutations and arterial calcifications." N. Engl. J. Med. 364:432-442(2011) [PubMed] [Europe PMC] [Abstract]
- "NT5E mutations that cause human disease are associated with intracellular mistrafficking of NT5E protein."PLoS ONE 9:E98568-E98568(2014) [PubMed] [Europe PMC] [Abstract]