Epithelial Cell Adhesion Molecule (EPCAM)

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CD326; TACSTD1; EGP; KSA; M4S1; MIC18; TROP1; HEGP2; ESA; Epithelial glycoprotein; Adenocarcinoma-associated antigen; Tumor Associated Calcium Signal Transducer 1

Epithelial Cell Adhesion Molecule (EPCAM)
The epithelial cell adhesion molecule (EpCAM, CD326) is a glycoprotein of ~40 kd that was originally identified as a marker for carcinoma, attributable to its high expression on rapidly proliferating tumors of epithelial origin. Normal epithelia express EpCAM at a variable but generally lower level than carcinoma cells. In early studies, EpCAM was proposed to be a cell-cell adhesion molecule.
However, recent insights revealed a more versatile role for EpCAM that is not limited only to cell adhesion but includes diverse processes such as signaling, cell migration, proliferation, and differentiation. Cell surface expression of EpCAM may actually prevent cell-cell adhesion.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB283Hu01 Recombinant Epithelial Cell Adhesion Molecule (EPCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB283Hu01 Polyclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) WB; IHC; ICC; IP.
MAB283Hu22 Monoclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) WB; IHC; ICC; IP.
MAB283Hu21 Monoclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) WB; IHC; ICC; IP.
Assay Kits SEB283Hu ELISA Kit for Epithelial Cell Adhesion Molecule (EPCAM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epithelial Cell Adhesion Molecule (EPCAM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epithelial Cell Adhesion Molecule (EPCAM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB283Po01 Recombinant Epithelial Cell Adhesion Molecule (EPCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB283Po01 Polyclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) WB; IHC
Assay Kits n/a CLIA Kit for Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB283Ga01 Recombinant Epithelial Cell Adhesion Molecule (EPCAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB283Ga01 Polyclonal Antibody to Epithelial Cell Adhesion Molecule (EPCAM) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Epithelial Cell Adhesion Molecule (EPCAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epithelial Cell Adhesion Molecule (EPCAM) ELISA Kit Customized Service Offer
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  14. "Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM."Front. Biosci. 13:5195-5201(2008) [PubMed] [Europe PMC] [Abstract]
  15. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
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  17. "Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells."J. Biol. Chem. 285:8719-8732(2010) [PubMed] [Europe PMC] [Abstract]
  18. "Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells."Stem Cells 28:29-35(2010) [PubMed] [Europe PMC] [Abstract]
  19. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
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