Extracellular Signal Regulated Kinase 1 (ERK1)

[Edit]

HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; MAPK3; ERT2; Mitogen-Activated Protein Kinase 3; Insulin-stimulated MAP2 kinase; Microtubule-associated protein 2 kinase

Extracellular Signal Regulated Kinase 1 (ERK1)

Mitogen-activated protein kinase 3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.

The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB357Hu01 Recombinant Extracellular Signal Regulated Kinase 1 (ERK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB357Hu01 Polyclonal Antibody to Extracellular Signal Regulated Kinase 1 (ERK1) WB; IHC; ICC; IP.
MAB357Hu22 Monoclonal Antibody to Extracellular Signal Regulated Kinase 1 (ERK1) WB; IHC; ICC; IP.
CAB357Hu22 Anti-Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody Loading Control of WB.
CAB357Hu01 Anti-Extracellular Signal Regulated Kinase 1 (ERK1) Polyclonal Antibody Loading Control of WB.
CAB357Mi01 Anti-Extracellular Signal Regulated Kinase 1 (ERK1) Polyclonal Antibody Loading Control of WB.
CAB357Mi22 Anti-Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody Loading Control of WB.
MAB357Hu21 Monoclonal Antibody to Extracellular Signal Regulated Kinase 1 (ERK1) WB; IHC; ICC; IP.
Assay Kits SEB357Hu ELISA Kit for Extracellular Signal Regulated Kinase 1 (ERK1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Extracellular Signal Regulated Kinase 1 (ERK1) Recombinant Protein Customized Service Offer
Antibodies CAB357Mi22 Anti-Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody Loading Control of WB.
Assay Kits n/a CLIA Kit for Extracellular Signal Regulated Kinase 1 (ERK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB357Ra01 Recombinant Extracellular Signal Regulated Kinase 1 (ERK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB357Ra01 Polyclonal Antibody to Extracellular Signal Regulated Kinase 1 (ERK1) WB; IHC; ICC; IP.
MAB357Ra21 Monoclonal Antibody to Extracellular Signal Regulated Kinase 1 (ERK1) WB; IHC; ICC; IP.
LAB357Ra81 FITC-Linked Polyclonal Antibody to Extracellular Signal Regulated Kinase 1 (ERK1) WB; IHC; ICC; IF.
CAB357Mi22 Anti-Extracellular Signal Regulated Kinase 1 (ERK1) Monoclonal Antibody Loading Control of WB.
Assay Kits SEB357Ra ELISA Kit for Extracellular Signal Regulated Kinase 1 (ERK1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1."Mol. Cell. Biol. 13:4679-4690(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]