Adenylate Cyclase 6 (ADCY6)

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ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Ca(2+)-inhibitable adenylyl cyclase

Adenylate Cyclase 6 (ADCY6)

Adenylate cyclase type 6 is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants.By Southern blot analysis of somatic cell hybrid DNAs, Gaudin et al. (1994) mapped the ADCY6 gene to chromosome 12. The homologous mouse gene is located on chromosome 15 in the F region.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB418Hu01Recombinant Adenylate Cyclase 6 (ADCY6)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB418Hu01Polyclonal Antibody to Adenylate Cyclase 6 (ADCY6)WB, ICC, IHC-P, IHC-F, ELISA
MAB418Hu21Monoclonal Antibody to Adenylate Cyclase 6 (ADCY6)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB418HuELISA Kit for Adenylate Cyclase 6 (ADCY6)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB418Mu01Recombinant Adenylate Cyclase 6 (ADCY6)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB418Mu01Polyclonal Antibody to Adenylate Cyclase 6 (ADCY6)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
Assay Kitsn/aCLIA Kit for Adenylate Cyclase 6 (ADCY6)CLIA Kit Customized Service Offer
n/aELISA Kit for Adenylate Cyclase 6 (ADCY6)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Adenylate Cyclase 6 (ADCY6)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Adenylate Cyclase 6 (ADCY6)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Adenylate Cyclase 6 (ADCY6)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Adenylate Cyclase 6 (ADCY6)CLIA Kit Customized Service Offer
n/aELISA Kit for Adenylate Cyclase 6 (ADCY6)ELISA Kit Customized Service Offer
  1. "Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues."Biochim. Biophys. Acta 1493:279-283(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 4:307-313(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line."Biochem. Biophys. Res. Commun. 192:311-318(1993) [PubMed] [Europe PMC] [Abstract]
  6. "Raf kinase activation of adenylyl cyclases: isoform-selective regulation."Mol. Pharmacol. 66:921-928(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]