Glycophosphatidylinositol (GPI)

Glycosylphosphatidylinositol is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification. It is composed of a phosphatidylinositol group linked through a carbohydrate containing linker to the C-terminal amino acid of a mature protein. The two fatty acids within the hydrophobic phosphatidyl-inositol group anchor the protein to the cell membrane. Glypiated proteins contain a signal peptide, thus directing them into the endoplasmic reticulum (ER). The C-terminus is composed of hydrophobic amino acids which stay inserted in the ER membrane. The hydrophobic end is then cleaved off and replaced by the GPI-anchor. As the protein processes through the secretory pathway, it is transferred via vesicles to the Golgi apparatus and finally to the extracellular space where it remains attached to the exterior leaflet of the cell membrane.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Glycophosphatidylinositol (GPI) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycophosphatidylinositol (GPI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycophosphatidylinositol (GPI) Polyclonal Antibody Customized Service Offer
Assay Kits CEB606Hu ELISA Kit for Glycophosphatidylinositol (GPI) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Glycophosphatidylinositol (GPI) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycophosphatidylinositol (GPI) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycophosphatidylinositol (GPI) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycophosphatidylinositol (GPI) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycophosphatidylinositol (GPI) ELISA Kit Customized Service Offer