Chemokine (C-X-C Motif) Ligand 27 (CCL27)

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CTACK; ILC; SCYA27; ALP; Skinkine; ESkine; PESKY; CTAK; Cutaneous T-Cell Attracting Chemokine; Small Inducible Cytokine Subfamily A Member 27; IL-11 R-alpha-locus chemokine

Chemokine (C-X-C Motif) Ligand 27 (CCL27)

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. The skin-associated chemokine CCL27 has a role in T cell-mediated skin inflammation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB651Hu01 Recombinant Chemokine (C-X-C Motif) Ligand 27 (CCL27) Positive Control; Immunogen; SDS-PAGE; WB.
APB651Hu01 Active Chemokine (C-X-C Motif) Ligand 27 (CCL27) Cell culture; Activity Assays.
EPB651Hu61 Eukaryotic Chemokine (C-X-C Motif) Ligand 27 (CCL27) Positive Control; Immunogen; SDS-PAGE; WB.
APB651Hu61 Active Chemokine (C-X-C Motif) Ligand 27 (CCL27) Cell culture; Activity Assays.
Antibodies PAB651Hu01 Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) WB; IHC; ICC; IP.
MAB651Hu22 Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) WB; IHC; ICC; IP.
LAB651Hu71 Biotin-Linked Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) WB; IHC; ICC.
LAB651Hu81 FITC-Linked Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) WB; IHC; ICC; IF.
MAB651Hu21 Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) WB; IHC; ICC; IP.
Assay Kits SEB651Hu ELISA Kit for Chemokine (C-X-C Motif) Ligand 27 (CCL27) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chemokine (C-X-C Motif) Ligand 27 (CCL27) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chemokine (C-X-C Motif) Ligand 27 (CCL27) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine (C-X-C Motif) Ligand 27 (CCL27) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Chemokine (C-X-C Motif) Ligand 27 (CCL27) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Chemokine (C-X-C Motif) Ligand 27 (CCL27) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Chemokine (C-X-C Motif) Ligand 27 (CCL27) CLIA Kit Customized Service Offer
n/a ELISA Kit for Chemokine (C-X-C Motif) Ligand 27 (CCL27) ELISA Kit Customized Service Offer
  1. "Molecular cloning of a novel CC chemokine, interleukin-11 receptor alpha-locus chemokine (ILC), which is located on chromosome 9p13 and a potential homologue of a CC chemokine encoded by molluscum contagiosum virus."FEBS Lett. 460:544-548(1999) [PubMed] [Europe PMC] [Abstract]
  2. "CTACK, a skin-associated chemokine that preferentially attracts skin-homing memory T cells."Proc. Natl. Acad. Sci. U.S.A. 96:14470-14475(1999) [PubMed] [Europe PMC] [Abstract]
  3. "The orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC)."J. Immunol. 164:3465-3470(2000) [PubMed] [Europe PMC] [Abstract]
  4. "NMR analysis of the structure, dynamics, and unique oligomerization properties of the chemokine CCL27."J. Biol. Chem. 285:14424-14437(2010) [PubMed] [Europe PMC] [Abstract]