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Interleukin 21 (IL-21), is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. This cytokine induces cell division/proliferation in its target cells. IL-21 elicits its effects on immune cells by interacting with a cell surface receptor known as the interleukin 21 receptor, IL-21R, that is expressed in bone marrow cells and various lymphocytes.
IL-21 is expressed in activated human CD4+ T cells but not in most other tissues. In addition, IL-21 expression is up-regulated in Th2 and Th17 subsets of T helper cells, as well as T follicular cells. Furthermore IL-21 is expressed in NK T cells regulating the function of these cells.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB688Hu01 | Recombinant Interleukin 21 (IL21) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB688Hu02 | Recombinant Interleukin 21 (IL21) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| APB688Hu01 | Active Interleukin 21 (IL21) | Cell culture; Activity Assays. | |
| APB688Hu61 | Active Interleukin 21 (IL21) | Cell culture; Activity Assays. | |
| Antibodies | PAB688Hu01 | Polyclonal Antibody to Interleukin 21 (IL21) | WB; IHC |
| MAB688Hu22 | Monoclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC; IP. | |
| LAB688Hu71 | Biotin-Linked Polyclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC. | |
| LAB688Hu81 | FITC-Linked Polyclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC; IF. | |
| PAB688Hu02 | Polyclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB688Hu | ELISA Kit for Interleukin 21 (IL21) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB688Hu | CLIA Kit for Interleukin 21 (IL21) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB688Mu01 | Recombinant Interleukin 21 (IL21) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB688Mu02 | Recombinant Interleukin 21 (IL21) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAB688Mu01 | Polyclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC; IP. |
| PAB688Mu02 | Polyclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB688Mu | ELISA Kit for Interleukin 21 (IL21) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB688Mu | CLIA Kit for Interleukin 21 (IL21) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPB688Ra01 | Recombinant Interleukin 21 (IL21) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB688Ra61 | Active Interleukin 21 (IL21) | Cell culture; Activity Assays. | |
| Antibodies | PAB688Ra01 | Polyclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC; IP. |
| MAB688Ra21 | Monoclonal Antibody to Interleukin 21 (IL21) | WB; IHC; ICC; IP. | |
| Assay Kits | SEB688Ra | ELISA Kit for Interleukin 21 (IL21) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB688Ra | CLIA Kit for Interleukin 21 (IL21) | Chemiluminescent immunoassay for Antigen Detection. |
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