Mothers Against Decapentaplegic Homolog 4 (Smad4)

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DPC4; JIP; MADH4; Deletion target in pancreatic carcinoma 4

Mothers Against Decapentaplegic Homolog 4 (Smad4)
SMAD4 is a 552 amino acid protein involved in cell signaling. It belongs to the Darfwin family of proteins which modulate members of the TGFβ protein superfamily. It binds receptor regulated SMADs such as SMAD1 or SMAD2 and forms a complex that binds to DNA and serves as a transcription factor. It is the only known mammalian coSMAD. It is a homolog of the Drosophila protein: "Mothers against decapentaplegic".
The SMAD proteins are homologs of both the drosophila protein, mothers against decapentaplegic (MAD) and the C. elegans protein SMA. The name is a combination of the two. During Drosophila research, it was found that a mutation in the gene, MAD, in the mother, repressed the gene, decapentaplegic, in the embryo.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB925Hu01Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB925Hu01Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4)WB, ICC, IHC-P, IHC-F, ELISA
MAB925Hu22Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB925HuELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB925Mu01Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB925Mu01Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4)CLIA Kit Customized Service Offer
n/aELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Mothers Against Decapentaplegic Homolog 4 (Smad4)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4)Polyclonal Antibody Customized Service Offer
Assay KitsSEB925RaELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4)Enzyme-linked immunosorbent assay for Antigen Detection
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