Creatine Kinase, Brain (CKB)

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CK-BB; CKBB; CK-B; CK-1

Creatine Kinase, Brain (CKB)
Brain-type creatine kinase consists of a homodimer of two identical brain-type CK-B subunits. BB-CK is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CK-BB forms tightly coupled microcompartments for in situ regeneration of ATP that has been used up.
The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine or between phospho-creatine (PCr) and ADP. Its functional entity is a homodimer (CK-BB) in brain, smooth muscle as well as in other tissues and cells such as neuronal cells, retina, kidney, bone etc.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC030Hu01Recombinant Creatine Kinase, Brain (CKB)SDS-PAGE; WB; ELISA; IP.
APC030Hu01Active Creatine Kinase, Brain (CKB)Cell culture; Activity Assays; In vivo assays.
AntibodiesPAC030Hu01Polyclonal Antibody to Creatine Kinase, Brain (CKB)WB, ICC, IHC-P, IHC-F, ELISA
MAC030Hu22Monoclonal Antibody to Creatine Kinase, Brain (CKB)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC030HuELISA Kit for Creatine Kinase, Brain (CKB)Enzyme-linked immunosorbent assay for Antigen Detection
SCC030HuCLIA Kit for Creatine Kinase, Brain (CKB)Chemiluminescent immunoassay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC030Mu01Recombinant Creatine Kinase, Brain (CKB)SDS-PAGE; WB; ELISA; IP.
NPC030Mu01Native Creatine Kinase, Brain (CKB)SDS-PAGE; WB; ELISA; IP.
RPC030Mu02Recombinant Creatine Kinase, Brain (CKB)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC030Mu01Polyclonal Antibody to Creatine Kinase, Brain (CKB)WB, ICC, IHC-P, IHC-F, ELISA
PAC030Mu02Polyclonal Antibody to Creatine Kinase, Brain (CKB)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC030MuELISA Kit for Creatine Kinase, Brain (CKB)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC030Ra01Recombinant Creatine Kinase, Brain (CKB)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC030Ra01Polyclonal Antibody to Creatine Kinase, Brain (CKB)WB, ICC, IHC-P, IHC-F, ELISA
LAC030Ra71Biotin-Linked Polyclonal Antibody to Creatine Kinase, Brain (CKB)IHC;WB;ELISA
MAC030Ra21Monoclonal Antibody to Creatine Kinase, Brain (CKB)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC030RaELISA Kit for Creatine Kinase, Brain (CKB)Enzyme-linked immunosorbent assay for Antigen Detection
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  2. "Structure and expression of the human creatine kinase B gene."Genomics 1:126-137(1987) [PubMed] [Europe PMC] [Abstract]
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  8. "Protein analysis of human maculae in relation to age-related maculopathy."Lab. Invest. 73:267-272(1995) [PubMed] [Europe PMC] [Abstract]