Major Histocompatibility Complex Class I C (MHCC)

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MHC-C;; HLAC; HLA-JY3; HLC-C; HLA-C; PSORS1 Leukocyte Antigen C; HLA class I histocompatibility antigen, Cw-7 alpha chain

Major Histocompatibility Complex Class I C (MHCC)
HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC086Hu01Recombinant Major Histocompatibility Complex Class I C (MHCC)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC086Hu01Polyclonal Antibody to Major Histocompatibility Complex Class I C (MHCC)WB, ICC, IHC-P, IHC-F, ELISA
MAC086Hu22Monoclonal Antibody to Major Histocompatibility Complex Class I C (MHCC)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Major Histocompatibility Complex Class I C (MHCC)CLIA Kit Customized Service Offer
n/aELISA Kit for Major Histocompatibility Complex Class I C (MHCC)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Major Histocompatibility Complex Class I C (MHCC)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Major Histocompatibility Complex Class I C (MHCC)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Major Histocompatibility Complex Class I C (MHCC)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Major Histocompatibility Complex Class I C (MHCC)CLIA Kit Customized Service Offer
n/aELISA Kit for Major Histocompatibility Complex Class I C (MHCC)ELISA Kit Customized Service Offer
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