Major Histocompatibility Complex Class I B (MHCB)

[Edit]

MHC-B; HLA-B; HLAB; AS; SPDA1; Leukocyte Antigen B; Ankylosing Spondylitis; HLA class I histocompatibility antigen, B-7 alpha chain

Major Histocompatibility Complex Class I B (MHCB)
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria.
The HLA-B gene has many different normal variations, allowing each person's immune system to react to a wide range of foreign invaders. Hundreds of versions (alleles) of HLA-B are known, each of which is given a particular number (such as HLA-B27). Closely related alleles are categorized together; for example, at least 28 very similar alleles are subtypes of HLA-B27.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC092Hu01 Recombinant Major Histocompatibility Complex Class I B (MHCB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC092Hu01 Polyclonal Antibody to Major Histocompatibility Complex Class I B (MHCB) WB; IHC; ICC; IP.
MAC092Hu21 Monoclonal Antibody to Major Histocompatibility Complex Class I B (MHCB) WB
Assay Kits SEC092Hu ELISA Kit for Major Histocompatibility Complex Class I B (MHCB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Class I B (MHCB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Class I B (MHCB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Class I B (MHCB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Class I B (MHCB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Class I B (MHCB) ELISA Kit Customized Service Offer
  1. "Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification."Proc. Natl. Acad. Sci. U.S.A. 87:2833-2837(1990) [PubMed] [Europe PMC] [Abstract]
  2. "Diversity of class I HLA molecules: functional and evolutionary interactions with T cells."Cold Spring Harb. Symp. Quant. Biol. 54:529-543(1989) [PubMed] [Europe PMC] [Abstract]
  3. "Structure and polymorphism of class I MHC antigen mRNA."Immunogenetics 22:101-121(1985) [PubMed] [Europe PMC] [Abstract]
  4. "Complete nucleotide sequence of HLA-B*0703, a B7-variant (BPOT)."Hum. Immunol. 38:159-162(1993) [PubMed] [Europe PMC] [Abstract]
  5. "Definition of a new HLA-B7 subtype (B*0704) by isoelectric focusing, family studies and DNA sequence analysis."Tissue Antigens 45:322-327(1995) [PubMed] [Europe PMC] [Abstract]
  6. "Structure of a novel subtype of B7 (B*0705) isolated from a Chinese individual."Tissue Antigens 44:318-321(1994) [PubMed] [Europe PMC] [Abstract]
  7. "Alloreactive cytotoxic T-lymphocyte-defined HLA-B7 subtypes differ in peptide antigen presentation."Immunogenetics 43:27-37(1996) [PubMed] [Europe PMC] [Abstract]
  8. "Haplotypic association of two new HLA class I alleles: Cw*15052 and B*0706: evolutionary relationships of HLA-Cw*15 alleles."Tissue Antigens 47:329-332(1996) [PubMed] [Europe PMC] [Abstract]
  9. "Cloning and sequencing full-length HLA-B and -C genes."Tissue Antigens 61:20-48(2003) [PubMed] [Europe PMC] [Abstract]
  10. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  11. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  12. "Characterisation of a new HLA-B allele, HLA-B*0724."Tissue Antigens 57:471-473(2001) [PubMed] [Europe PMC] [Abstract]
  13. "Complete amino acid sequence of a papain-solubilized human histocompatibility antigen, HLA-B7. 2. Sequence determination and search for homologies."Biochemistry 18:5711-5720(1979) [PubMed] [Europe PMC] [Abstract]
  14. "Free major histocompatibility complex class I heavy chain is preferentially targeted for degradation by human T-cell leukemia/lymphotropic virus type 1 p12(I) protein."J. Virol. 75:6086-6094(2001) [PubMed] [Europe PMC] [Abstract]
  15. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  16. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]