Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1)

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HLA-DPA1; HLADPa1; HLA-DP1A; HLASB; HLA-SB alpha chain; Major Histocompatibility Complex,Class II,DP Alpha 1

Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1)

Major histocompatibility complex, class II, DP alpha 1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Major Histocompatibility Complex Class II DP Alpha 1 (MHCDPa1) ELISA Kit Customized Service Offer
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  20. "MHC class II molecules on the move for successful antigen presentation."EMBO J. 27:1-5(2008) [PubMed] [Europe PMC] [Abstract]
  21. "Autophagy in MHC class II presentation: sampling from within."Immunity 26:1-3(2007) [PubMed] [Europe PMC] [Abstract]
  22. "MHC class II transport at a glance."J. Cell Sci. 122:1-4(2009) [PubMed] [Europe PMC] [Abstract]
  23. "CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract."World J. Gastroenterol. 15:2855-2861(2009) [PubMed] [Europe PMC] [Abstract]
  24. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  25. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]