Breakpoint Cluster Region (BCR)

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ALL; BCR/FGFR1; BCR1; CML; FGFR1/BCR; PHL; Renal carcinoma antigen NY-REN-26

Breakpoint Cluster Region (BCR)

The BCR gene is one of the two genes in the bcr-abl complex, which is associated with the Philadelphia chromosome.A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC328Hu01 Recombinant Breakpoint Cluster Region (BCR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC328Hu01 Polyclonal Antibody to Breakpoint Cluster Region (BCR) WB; IHC; ICC; IP.
Assay Kits SEC328Hu ELISA Kit for Breakpoint Cluster Region (BCR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC328Mu01 Recombinant Breakpoint Cluster Region (BCR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC328Mu01 Polyclonal Antibody to Breakpoint Cluster Region (BCR) WB; IHC; ICC; IP.
Assay Kits SEC328Mu ELISA Kit for Breakpoint Cluster Region (BCR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Breakpoint Cluster Region (BCR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Breakpoint Cluster Region (BCR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Breakpoint Cluster Region (BCR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Breakpoint Cluster Region (BCR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Breakpoint Cluster Region (BCR) ELISA Kit Customized Service Offer
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