Breakpoint Cluster Region (BCR)

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ALL; BCR/FGFR1; BCR1; CML; FGFR1/BCR; PHL; Renal carcinoma antigen NY-REN-26

Breakpoint Cluster Region (BCR)
The BCR gene is one of the two genes in the bcr-abl complex, which is associated with the Philadelphia chromosome.A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC328Hu01Recombinant Breakpoint Cluster Region (BCR)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC328Hu01Polyclonal Antibody to Breakpoint Cluster Region (BCR)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Breakpoint Cluster Region (BCR)CLIA Kit Customized Service Offer
n/aELISA Kit for Breakpoint Cluster Region (BCR)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC328Mu01Recombinant Breakpoint Cluster Region (BCR)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC328Mu01Polyclonal Antibody to Breakpoint Cluster Region (BCR)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Breakpoint Cluster Region (BCR)CLIA Kit Customized Service Offer
n/aELISA Kit for Breakpoint Cluster Region (BCR)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Breakpoint Cluster Region (BCR)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Breakpoint Cluster Region (BCR)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Breakpoint Cluster Region (BCR)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Breakpoint Cluster Region (BCR)CLIA Kit Customized Service Offer
n/aELISA Kit for Breakpoint Cluster Region (BCR)ELISA Kit Customized Service Offer
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