Cullin 1 (CUL1)
Cullin 1 is a protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, it serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. This protein is a part of a SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. It also interacts with RNF7. Part of a complex with TIP120A/CAND1 and RBX1. The unneddylated form interacts with TIP120A/CAND1 and the interaction negatively regulates the association with SKP1 in the SCF complex. Interacts with COPS2.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC412Hu01Recombinant Cullin 1 (CUL1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC412Hu01Polyclonal Antibody to Cullin 1 (CUL1)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Cullin 1 (CUL1)CLIA Kit Customized Service Offer
n/aELISA Kit for Cullin 1 (CUL1)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Cullin 1 (CUL1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Cullin 1 (CUL1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Cullin 1 (CUL1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Cullin 1 (CUL1)CLIA Kit Customized Service Offer
n/aELISA Kit for Cullin 1 (CUL1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Cullin 1 (CUL1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Cullin 1 (CUL1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Cullin 1 (CUL1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Cullin 1 (CUL1)CLIA Kit Customized Service Offer
n/aELISA Kit for Cullin 1 (CUL1)ELISA Kit Customized Service Offer
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