Galanin Receptor 1 (GALR1)

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GALNR; GALNR1

Galanin Receptor 1 (GALR1)
Galanin receptor 1is a G-protein.The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Galanin Receptor 1 (GALR1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Galanin Receptor 1 (GALR1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Galanin Receptor 1 (GALR1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Galanin Receptor 1 (GALR1)CLIA Kit Customized Service Offer
n/aELISA Kit for Galanin Receptor 1 (GALR1)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Galanin Receptor 1 (GALR1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Galanin Receptor 1 (GALR1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Galanin Receptor 1 (GALR1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Galanin Receptor 1 (GALR1)CLIA Kit Customized Service Offer
n/aELISA Kit for Galanin Receptor 1 (GALR1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Galanin Receptor 1 (GALR1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Galanin Receptor 1 (GALR1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Galanin Receptor 1 (GALR1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Galanin Receptor 1 (GALR1)CLIA Kit Customized Service Offer
n/aELISA Kit for Galanin Receptor 1 (GALR1)ELISA Kit Customized Service Offer
  1. "Molecular cloning of a functional human galanin receptor."Proc. Natl. Acad. Sci. U.S.A. 91:9780-9783(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning, chromosomal location, and transcriptional regulation of the human galanin-1 receptor gene (GALN1R)."Biochem. Biophys. Res. Commun. 241:558-564(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Structural organization of the mouse and human GALR1 galanin receptor genes (Galnr and GALNR) and chromosomal localization of the mouse gene."Genomics 45:496-508(1997) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 18." Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]