Ryanodine Receptor 1, Skeletal (RYR1)

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CCO; MHS; MHS1; RYDR; RYR; SKRR; Central Core Disease Of Muscle; Skeletal muscle calcium release channel

Ryanodine Receptor 1, Skeletal (RYR1)
Ryanodine receptor 1 is a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
Communication between transverse-tubules and sarcoplasmic reticulum. Contraction of skeletal muscle is triggered by release of calcium ions from SR following depolarization of T-tubules.Skeletal muscle and brain (cerebellum and hippocampus).

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC773Hu01Recombinant Ryanodine Receptor 1, Skeletal (RYR1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC773Hu01Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1)WB, ICC, IHC-P, IHC-F, ELISA
MAC773Hu21Monoclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC773HuELISA Kit for Ryanodine Receptor 1, Skeletal (RYR1)Enzyme-linked immunosorbent assay

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC773Mu01Recombinant Ryanodine Receptor 1, Skeletal (RYR1)SDS-PAGE; WB; ELISA; IP.
RPC773Mu02Recombinant Ryanodine Receptor 1, Skeletal (RYR1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC773Mu01Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1)WB, ICC, IHC-P, IHC-F, ELISA
PAC773Mu02Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC773MuELISA Kit for Ryanodine Receptor 1, Skeletal (RYR1)Enzyme-linked immunosorbent assay

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC773Ra01Recombinant Ryanodine Receptor 1, Skeletal (RYR1)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC773Ra01Polyclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1)WB, ICC, IHC-P, IHC-F, ELISA
MAC773Ra21Monoclonal Antibody to Ryanodine Receptor 1, Skeletal (RYR1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC773RaELISA Kit for Ryanodine Receptor 1, Skeletal (RYR1)Enzyme-linked immunosorbent assay
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