Reelin (RELN)

Reelin is a protein that helps regulate processes of neuronal migration and positioning in the developing brain. Besides this important role in early development, reelin continues to work in the adult brain. It modulates the synaptic plasticity by enhancing the induction and maintenance of long-term potentiation.

It also stimulates dendrite and dendritic spine development and regulates the continuing migration of neuroblasts generated in adult neurogenesis sites like subventricular and subgranular zones. It is found not only in the brain, but also in the spinal cord, blood, and other body organs and tissues. Reelin has been suggested to be implicated in pathogenesis of several brain diseases.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC775Hu01 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC775Hu03 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC775Hu02 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC775Hu04 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC775Hu05 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC775Hu01 Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
MAC775Hu22 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
PAC775Hu03 Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
PAC775Hu02 Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
PAC775Hu04 Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
MAC775Hu21 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
MAC775Hu24 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
MAC775Hu23 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
MAC775Hu27 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
MAC775Hu25 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
MAC775Hu29 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
Assay Kits SEC775Hu ELISA Kit for Reelin (RELN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC775Mu01 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC775Mu02 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC775Mu01 Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
PAC775Mu02 Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
Assay Kits SEC775Mu ELISA Kit for Reelin (RELN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC775Ra01 Recombinant Reelin (RELN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC775Ra01 Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
LAC775Ra71 Biotin-Linked Polyclonal Antibody to Reelin (RELN) WB; IHC; ICC.
MAC775Ra21 Monoclonal Antibody to Reelin (RELN) WB; IHC; ICC; IP.
Assay Kits SEC775Ra ELISA Kit for Reelin (RELN) Enzyme-linked immunosorbent assay for Antigen Detection.
SCC775Ra CLIA Kit for Reelin (RELN) Chemiluminescent immunoassay for Antigen Detection.
  1. "The human reelin gene: isolation, sequencing, and mapping on chromosome 7."Genome Res. 7:157-164(1997) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Evolutionarily conserved, alternative splicing of reelin during brain development."Exp. Neurol. 156:229-238(1999) [PubMed] [Europe PMC] [Abstract]
  5. "A decrease of reelin expression as a putative vulnerability factor in schizophrenia."Proc. Natl. Acad. Sci. U.S.A. 95:15718-15723(1998) [PubMed] [Europe PMC] [Abstract]
  6. "Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations."Nat. Genet. 26:93-96(2000) [PubMed] [Europe PMC] [Abstract]
  7. ErratumNat. Genet. 27:225-225(2001)
  8. "Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder." Mol. Psychiatry 6:150-159(2001) [PubMed] [Europe PMC] [Abstract]
  9. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]