Tripeptidyl Peptidase I (TPP1)

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CLN2; GIG1; LPIC; Tripeptidyl aminopeptidase; Lysosomal pepstatin-insensitive protease; Ceroid-Lipofuscinosis,Neuronal 2,Late Infantile; Cell growth-inhibiting gene 1 protein

Tripeptidyl Peptidase I (TPP1)
Tripeptidyl-peptidase 1 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity.
It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC828Hu01 Recombinant Tripeptidyl Peptidase I (TPP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC828Hu01 Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) WB; IHC; ICC; IP.
MAC828Hu22 Monoclonal Antibody to Tripeptidyl Peptidase I (TPP1) WB; IHC; ICC; IP.
Assay Kits SEC828Hu ELISA Kit for Tripeptidyl Peptidase I (TPP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC828Mu01 Recombinant Tripeptidyl Peptidase I (TPP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC828Mu02 Recombinant Tripeptidyl Peptidase I (TPP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC828Mu01 Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) WB; IHC; ICC; IP.
PAC828Mu02 Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) WB; IHC; ICC; IP.
Assay Kits SEC828Mu ELISA Kit for Tripeptidyl Peptidase I (TPP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tripeptidyl Peptidase I (TPP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tripeptidyl Peptidase I (TPP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tripeptidyl Peptidase I (TPP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tripeptidyl Peptidase I (TPP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tripeptidyl Peptidase I (TPP1) ELISA Kit Customized Service Offer
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