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Synapsin I (SYN1)

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SYN1a; SYN1b; SYNI; Brain protein 4.1

Synapsin I (SYN1)
CCC C883
HGNC 11494
MGI 98460
PubMed 21441247
RGD 3797
UniProt P17600
Wiki SYN1
The synapsin I protein is a member of the synapsin family that are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases.The phosphoprotein plays a role in regulation of axonogenesis and synaptogenesis.
The protein serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal.Synapsin I is found in two isoforms of the protein, Synapsin Ia and Synapsin Ib, with Synapsin Ib being a slightly shorter version of the protein.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synapsin I (SYN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synapsin I (SYN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synapsin I (SYN1) Polyclonal Antibody Customized Service Offer
Assay Kits SEC883Hu ELISA Kit for Synapsin I (SYN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC883Mu01 Recombinant Synapsin I (SYN1) Positive Control; Immunogen; SDS-PAGE; WB.
RPC883Mu02 Recombinant Synapsin I (SYN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC883Mu01 Polyclonal Antibody to Synapsin I (SYN1) WB; IHC; ICC; IP.
PAC883Mu02 Polyclonal Antibody to Synapsin I (SYN1) WB; IHC; ICC; IP.
Assay Kits SEC883Mu ELISA Kit for Synapsin I (SYN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC883Ra01 Recombinant Synapsin I (SYN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC883Ra01 Polyclonal Antibody to Synapsin I (SYN1) WB; IHC; ICC; IP.
MAC883Ra21 Monoclonal Antibody to Synapsin I (SYN1) WB; IHC; ICC; IP.
Assay Kits SEC883Ra ELISA Kit for Synapsin I (SYN1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The structure of the human synapsin I gene and protein."J. Biol. Chem. 265:7849-7852(1990) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The 5'-flanking region of the synapsin I gene. A G+C-rich, TATA- and CAAT-less, phylogenetically conserved sequence with cell type-specific promoter function."J. Biol. Chem. 265:14932-14937(1990) [PubMed] [Europe PMC] [Abstract]
  4. "Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy."J. Med. Genet. 41:183-187(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Phosphoproteomic analysis of synaptosomes from human cerebral cortex."J. Proteome Res. 4:306-315(2005) [PubMed] [Europe PMC] [Abstract]
  6. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]