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Triadin, also known as TRDN, associated with the release of Calcium ions from the sarcoplasmic reticulum triggering muscular contraction through calcium-induced calcium release.
Triadin, a protein found in rabbit triadic junctions, is intrinsic to the terminal cisternae and is closely associated with the RYR1. The predicted 729-amino acid human protein shares 95% identity with rabbit triadin. Like the rabbit protein, human triadin contains a small cytoplasmic domain and a single transmembrane domain. Human triadin has a calculated pI of 9.3 and molecular mass of 82 kD. However, on Western blots, its apparent molecular mass is 117 kD.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Triadin (TRDN) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Triadin (TRDN) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Triadin (TRDN) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Triadin (TRDN) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Triadin (TRDN) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD033Mu01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAD033Mu01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Triadin (TRDN) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Triadin (TRDN) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD033Ra01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAD033Ra01 | Polyclonal Antibody to Triadin (TRDN) | WB |
| Assay Kits | n/a | CLIA Kit for Triadin (TRDN) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Triadin (TRDN) | ELISA Kit Customized Service Offer |
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- "Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human." Hum. Mol. Genet. 21:2759-2767(2012) [PubMed] [Europe PMC] [Abstract]
- "Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum."Biochem. J. 458:407-417(2014) [PubMed] [Europe PMC] [Abstract]