Epstein Barr Virus Induced Protein 3 (EBI3)

[Edit]

IL27B; IL27-B; Interleukin 27B; Epstein-Barr virus-induced gene 3 protein; EBV-induced gene 3 protein

Epstein Barr Virus Induced Protein 3 (EBI3)
Epstein-Barr virus induced gene 3was identified by the induction of its expression in B lymphocytes by Epstein-Barr virus infection. The protein encoded by this gene is a secreted glycoprotein, which is a member of the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). It plays a role in regulating cell-mediated immune responses.EBI3 is a subunit in 2 distinct heterodimeric cytokines: interleukin-27 (IL27) and IL35.
IL27 is composed of p28 (IL27) and EBI3. IL27 can trigger signaling in T cells, B cells, and myeloid cells. IL35, an inhibitory cytokine involved in regulatory T-cell function, is composed of EBI3 and the p35 subunit of IL12.Interleukin-27 (IL-27)is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (IL-27B) and IL27-p28 (known as IL-30).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD206Hu01 Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD206Hu01 Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) WB; IHC; ICC; IP.
MAD206Hu22 Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) WB; IHC; ICC; IP.
LAD206Hu71 Biotin-Linked Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) WB; IHC; ICC.
LAD206Hu81 FITC-Linked Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) WB; IHC; ICC; IF.
MAD206Hu24 Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) WB; IHC; ICC; IP.
Assay Kits SCD206Hu CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD206Mu01 Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) Positive Control; Immunogen; SDS-PAGE; WB.
RPD206Mu02 Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD206Mu01 Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) WB; IHC; ICC; IP.
PAD206Mu02 Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) WB; IHC; ICC; IP.
Assay Kits SED206Mu ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) Enzyme-linked immunosorbent assay for Antigen Detection.
SCD206Mu CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) ELISA Kit Customized Service Offer
  1. "A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes."J. Virol. 70:1143-1153(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin."Proc. Natl. Acad. Sci. U.S.A. 94:12041-12046(1997) [PubMed] [Europe PMC] [Abstract]
  5. "IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells." Immunity 16:779-790(2002) [PubMed] [Europe PMC] [Abstract]
  6. "The biology and therapeutic potential of interleukin 27."J. Mol. Med. 85:661-672(2007) [PubMed] [Europe PMC] [Abstract]