Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)

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CMD1S; CMH1; MPD1; MYHCB; Myopathy,Distal 1; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle beta isoform

Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)
MYH7 is a gene encoding a myosin heavy chain beta (MHC-β) isoform (slow twitch) expressed primarily in the heart.In early fetal development, MHC-β is predominately expressed in the ventricles, while MHC-α is predominantly expressed in the atria. In healthy adult hearts, MHC-α is predominantly expressed in the atria (>90%), while MHC-β (~50%) is expressed in the atria of failing adult hearts. In vitro studies have demonstrated that newly formed cardiac myocytes express MHC-β, and after prolonged (1-5 weeks) contractile activity MHC-α becomes detectable. An allelic variant of this gene is associated with approximately 40% of the cases of Hypertrophic cardiomyopathy (HCM). This condition is an autosomal-dominant disease, in which a single copy of the variant gene causes enlargement of the left ventricle of the heart.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPD418Hu01Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)SDS-PAGE; WB; ELISA; IP
AntibodiesPAD418Hu01Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)WB, ICC, IHC-P, IHC-F, ELISA
MAD418Hu21Monoclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)WB, ICC, IHC-P, IHC-F, ELISA
LAD418Hu81FITC-Linked Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)WB; ICC; IHC-P; IHC-F; IF; Flow Cyt; ELISA.
Assay KitsSED418HuELISA Kit for Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPD418Mu01Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)SDS-PAGE; WB; ELISA; IP.
RPD418Mu02Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAD418Mu01Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)WB, ICC, IHC-P, IHC-F, ELISA
PAD418Mu02Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSED418MuELISA Kit for Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPD418Ra01Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAD418Ra01Polyclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)WB, ICC, IHC-P, IHC-F, ELISA
MAD418Ra21Monoclonal Antibody to Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSED418RaELISA Kit for Myosin Heavy Chain 7, Cardiac Muscle, Beta (MYH7)Enzyme-linked immunosorbent assay for Antigen Detection
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  64. Unpublished observations (OCT-2004)
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