Glutathione Peroxidase 5 (GPX5)

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GSHPx-5; Epididymal Androgen Related Protein; Epididymal secretory glutathione peroxidase; Glutathione peroxidase 5; Epididymis-specific glutathione peroxidase-like protein

Glutathione Peroxidase 5 (GPX5)
GPX5 belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutathione Peroxidase 5 (GPX5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutathione Peroxidase 5 (GPX5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutathione Peroxidase 5 (GPX5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutathione Peroxidase 5 (GPX5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutathione Peroxidase 5 (GPX5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glutathione Peroxidase 5 (GPX5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glutathione Peroxidase 5 (GPX5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glutathione Peroxidase 5 (GPX5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glutathione Peroxidase 5 (GPX5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutathione Peroxidase 5 (GPX5) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD994Ra01 Recombinant Glutathione Peroxidase 5 (GPX5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD994Ra01 Polyclonal Antibody to Glutathione Peroxidase 5 (GPX5) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Glutathione Peroxidase 5 (GPX5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glutathione Peroxidase 5 (GPX5) ELISA Kit Customized Service Offer
  1. "The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract."Biochem. J. 333:5-9(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Crystal structure of human glutathione peroxidase 5."Submitted (FEB-2009) to the PDB data bank