Ephrin Type A Receptor 5 (EPHA5)

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TYRO4; CEK7; EHK1; HEK7; Brain-specific kinase; EPH homology kinase 1; EPH-like kinase 7

Ephrin Type A Receptor 5 (EPHA5)
EPH receptor A5 is a protein belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Almost exclusively expressed in the nervous system.Unlike most other receptor PTKs, HEK7 has a restricted pattern of expression; Fox et al. (1995) observed 6-kb and 9-kb mRNAs in human brain and weak expression of the 9-kb mRNA in placenta.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Ephrin Type A Receptor 5 (EPHA5)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Ephrin Type A Receptor 5 (EPHA5)CLIA Kit Customized Service Offer
n/aELISA Kit for Ephrin Type A Receptor 5 (EPHA5)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Ephrin Type A Receptor 5 (EPHA5)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Ephrin Type A Receptor 5 (EPHA5)CLIA Kit Customized Service Offer
n/aELISA Kit for Ephrin Type A Receptor 5 (EPHA5)ELISA Kit Customized Service Offer
  1. "Extensive splice variation and localization of the EHK-1 receptor tyrosine kinase in adult human brain and glial tumors."Brain Res. Mol. Brain Res. 46:17-24(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases."Oncogene 10:897-905(1995) [PubMed] [Europe PMC] [Abstract]
  5. "Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation."Neuron 14:973-981(1995) [PubMed] [Europe PMC] [Abstract]
  6. "Unified nomenclature for Eph family receptors and their ligands, the ephrins."Cell 90:403-404(1997) [PubMed] [Europe PMC] [Abstract]
  7. "Immunohistochemical localization of EphA5 in the adult human central nervous system."J. Histochem. Cytochem. 47:855-861(1999) [PubMed] [Europe PMC] [Abstract]
  8. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]