Guanylate Binding Protein 7 (GBP7)

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GBP4L; GTP-binding protein 7; Guanine nucleotide-binding protein 7; Guanylate-binding protein 4-like

Guanylate Binding Protein 7 (GBP7)
Guanylate-binding proteins, such as GBP7, are induced by interferon and hydrolyze GTP to both GDP and GMP.Olszewski et al. (2006) identified GBP7 within the GBP gene cluster on chromosome 1. The 639-amino acid GBP7 protein shares 74% and 81% identity with GBP6 and GBP4, respectively. All GBPs, including GBP7, have a conserved N-terminal globular GTP-binding domain containing 2 consensus sequences and a third T(L/V)RD sequence not found in other GTPases.
GBP7 lacks a C-terminal CaaX isoprenylation motif found in GBP1, GBP2, and GBP5. EST database analysis indicated that GBP7 expression was limited to eye, stomach, and uterus.Using RT-PCR, Tripal et al. (2007) detected expression of all GBPs except GBP6 and GBP7 in endothelial cells after stimulation with IFNG , TNF , or IL1B.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPE632Hu01Recombinant Guanylate Binding Protein 7 (GBP7)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAE632Hu01Polyclonal Antibody to Guanylate Binding Protein 7 (GBP7)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Guanylate Binding Protein 7 (GBP7)CLIA Kit Customized Service Offer
n/aELISA Kit for Guanylate Binding Protein 7 (GBP7)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Guanylate Binding Protein 7 (GBP7)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Guanylate Binding Protein 7 (GBP7)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Guanylate Binding Protein 7 (GBP7)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Guanylate Binding Protein 7 (GBP7)CLIA Kit Customized Service Offer
n/aELISA Kit for Guanylate Binding Protein 7 (GBP7)ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]