Filamin C Gamma (FLNC)

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ABP-280; ABP280A; ABPA; ABPL; FLN2; Actin Binding Protein 280; ABP-280-like protein; Actin-binding-like protein; Filamin-2

Filamin C Gamma (FLNC)
Filamin-C is one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross- linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z-disks in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE932Hu01 Recombinant Filamin C Gamma (FLNC) Positive Control; Immunogen; SDS-PAGE; WB.
RPE932Hu02 Recombinant Filamin C Gamma (FLNC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE932Hu01 Polyclonal Antibody to Filamin C Gamma (FLNC) WB; IHC; ICC; IP.
MAE932Hu21 Monoclonal Antibody to Filamin C Gamma (FLNC) WB; IHC; ICC; IP.
PAE932Hu02 Polyclonal Antibody to Filamin C Gamma (FLNC) WB; IHC; ICC; IP.
Assay Kits SEE932Hu ELISA Kit for Filamin C Gamma (FLNC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Filamin C Gamma (FLNC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Filamin C Gamma (FLNC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Filamin C Gamma (FLNC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Filamin C Gamma (FLNC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Filamin C Gamma (FLNC) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Filamin C Gamma (FLNC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Filamin C Gamma (FLNC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Filamin C Gamma (FLNC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Filamin C Gamma (FLNC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Filamin C Gamma (FLNC) ELISA Kit Customized Service Offer
  1. "Molecular cloning of human ABPL, an actin-binding protein homologue."Biochem. Biophys. Res. Commun. 251:914-919(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family."Hum. Genet. 107:597-611(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization of muscle filamin isoforms suggests a possible role of gamma-filamin/ABP-L in sarcomeric Z-disc formation."Cell Motil. Cytoskeleton 45:149-162(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Filamin 2 (FLN2): a muscle-specific sarcoglycan interacting protein."J. Cell Biol. 148:115-126(2000) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]