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Leukocyte Cell Derived Chemotaxin 2 (LECT2)

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Chm-II; Chm2

Leukocyte Cell Derived Chemotaxin 2 (LECT2)
CCC F541
HGNC 6550
MGI 1278342
PubMed 21394108
RGD 1305404
UniProt O14960
Wiki LECT2
Leukocyte cell-derived chemotaxin-2 is a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis. Neutrophils migrate in response to increasing concentrations of chemotactic factors released from inflammatory sites. From the culture fluid of a human T-cell leukemia cell line (SKW-3), Yamagoe et al. (1996) isolated a 16-kD secreted protein with neutrophil chemotactic activity and designated it LECT2. They purified the protein and determined the amino acid sequence.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF541Hu01 Recombinant Leukocyte Cell Derived Chemotaxin 2 (LECT2) Positive Control; Immunogen; SDS-PAGE; WB.
EPF541Hu61 Eukaryotic Leukocyte Cell Derived Chemotaxin 2 (LECT2) Positive Control; Immunogen; SDS-PAGE; WB.
APF541Hu61 Active Leukocyte Cell Derived Chemotaxin 2 (LECT2) Cell culture; Activity Assays.
Antibodies PAF541Hu01 Polyclonal Antibody to Leukocyte Cell Derived Chemotaxin 2 (LECT2) WB; IHC; ICC; IP.
MAF541Hu21 Monoclonal Antibody to Leukocyte Cell Derived Chemotaxin 2 (LECT2) WB; IHC; ICC; IP.
Assay Kits SEF541Hu ELISA Kit for Leukocyte Cell Derived Chemotaxin 2 (LECT2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF541Mu01 Recombinant Leukocyte Cell Derived Chemotaxin 2 (LECT2) Positive Control; Immunogen; SDS-PAGE; WB.
RPF541Mu02 Recombinant Leukocyte Cell Derived Chemotaxin 2 (LECT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF541Mu01 Polyclonal Antibody to Leukocyte Cell Derived Chemotaxin 2 (LECT2) WB; IHC; ICC; IP.
PAF541Mu02 Polyclonal Antibody to Leukocyte Cell Derived Chemotaxin 2 (LECT2) WB; IHC; ICC; IP.
Assay Kits SEF541Mu ELISA Kit for Leukocyte Cell Derived Chemotaxin 2 (LECT2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF541Ra01 Recombinant Leukocyte Cell Derived Chemotaxin 2 (LECT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF541Ra01 Polyclonal Antibody to Leukocyte Cell Derived Chemotaxin 2 (LECT2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Leukocyte Cell Derived Chemotaxin 2 (LECT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leukocyte Cell Derived Chemotaxin 2 (LECT2) ELISA Kit Customized Service Offer
  1. "Molecular cloning of human and bovine LECT2 having a neutrophil chemotactic activity and its specific expression in the liver."Biochim. Biophys. Acta 1396:105-113(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning, structural characterization, and chromosomal mapping of the human LECT2 gene."Genomics 48:324-329(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Systemic expression of a newly recognized protein, LECT2, in the human body."Pathol. Int. 48:882-886(1998) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Purification and primary amino acid sequence of a novel neutrophil chemotactic factor LECT2."Immunol. Lett. 52:9-13(1996) [PubMed] [Europe PMC] [Abstract]
  8. "Identification and assignment of three disulfide bonds in mammalian leukocyte cell-derived chemotaxin 2 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry."Biosci. Trends 3:139-143(2009) [PubMed] [Europe PMC] [Abstract]