Neuropeptide Y Receptor Y2 (NPY2R)

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NPY-Y2 receptor

Neuropeptide Y Receptor Y2 (NPY2R)
Neuropeptide Y (NPY) signals through a family of G protein-coupled receptors present in the brain and sympathetic neurons. At least 3 types of neuropeptide Y receptor have been defined on the basis of pharmacologic criteria, tissue distribution, and structure of the encoding gene. Rose et al. (1995) reported the expression cloning in COS cells of a cDNA for the human type 2 receptor, NPY2R. Transfected cells showed high affinity for NPY, peptide YY (PYY), and a fragment of NPY including amino acids 13 to 36. The predicted 381-amino acid protein has 7 transmembrane domains characteristic of G protein-coupled receptors and is only 31% identical to the human Y1 receptor (NPY1R). A 4-kb mRNA was detected on Northern blots of tissue samples from several regions of the nervous system.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPG000Hu01Recombinant Neuropeptide Y Receptor Y2 (NPY2R)SDS-PAGE; WB; ELISA; IP.
AntibodiesMAG000Hu21Monoclonal Antibody to Neuropeptide Y Receptor Y2 (NPY2R)WB, ICC, IHC-P, IHC-F, ELISA
PAG000Hu01Polyclonal Antibody to Neuropeptide Y Receptor Y2 (NPY2R)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEG000HuELISA Kit for Neuropeptide Y Receptor Y2 (NPY2R)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPG000Mu01Recombinant Neuropeptide Y Receptor Y2 (NPY2R)SDS-PAGE; WB; ELISA; IP.
RPG000Mu02Recombinant Neuropeptide Y Receptor Y2 (NPY2R)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAG000Mu01Polyclonal Antibody to Neuropeptide Y Receptor Y2 (NPY2R)WB, ICC, IHC-P, IHC-F, ELISA
PAG000Mu02Polyclonal Antibody to Neuropeptide Y Receptor Y2 (NPY2R)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEG000MuELISA Kit for Neuropeptide Y Receptor Y2 (NPY2R)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPG000Ra01Recombinant Neuropeptide Y Receptor Y2 (NPY2R)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAG000Ra01Polyclonal Antibody to Neuropeptide Y Receptor Y2 (NPY2R)WB, ICC, IHC-P, IHC-F, ELISA
MAG000Ra21Monoclonal Antibody to Neuropeptide Y Receptor Y2 (NPY2R)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEG000RaELISA Kit for Neuropeptide Y Receptor Y2 (NPY2R)Enzyme-linked immunosorbent assay for Antigen Detection
  1. "Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype."J. Biol. Chem. 270:26758-26761(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Expression cloning of a human brain neuropeptide Y Y2 receptor."Mol. Pharmacol. 49:224-228(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor."J. Biol. Chem. 270:22661-22664(1995) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors."Proc. Natl. Acad. Sci. U.S.A. 93:4661-4665(1996) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of the human type 2 neuropeptide Y receptor gene (NPY2R) and localization to the chromosome 4q region containing the type 1 neuropeptide Y receptor gene."Genomics 38:392-398(1996) [PubMed] [Europe PMC] [Abstract]
  6. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]