Forkhead Box Protein G1 (FOXG1)

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FOX-G1; BF1; FKH2; FKHL1; FKHL4; HBF-1; HFK1; QIN; FKHL2; FOXG1B; FOXG1C; FKHL3; FOXG1A; HFK3; HBF-3; Brain factor 1; Forkhead-related protein FKHL1

Forkhead Box Protein G1 (FOXG1)
FOXG1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.
HFK1 was found to be highly conserved among mammalian species and possibly among birds. Northern blot analysis detected a 3.2-kb transcript in human and mouse fetal brain and adult mouse brain. In situ hybridization with sections of mouse embryo and human fetal brain demonstrated that HFK1 expression was restricted to the neuronal cells in the telencephalon, with strong expression in the developing dentate gyrus and hippocampus.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Forkhead Box Protein G1 (FOXG1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Forkhead Box Protein G1 (FOXG1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Forkhead Box Protein G1 (FOXG1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Forkhead Box Protein G1 (FOXG1)CLIA Kit Customized Service Offer
n/aELISA Kit for Forkhead Box Protein G1 (FOXG1)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Forkhead Box Protein G1 (FOXG1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Forkhead Box Protein G1 (FOXG1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Forkhead Box Protein G1 (FOXG1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Forkhead Box Protein G1 (FOXG1)CLIA Kit Customized Service Offer
n/aELISA Kit for Forkhead Box Protein G1 (FOXG1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Forkhead Box Protein G1 (FOXG1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Forkhead Box Protein G1 (FOXG1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Forkhead Box Protein G1 (FOXG1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Forkhead Box Protein G1 (FOXG1)CLIA Kit Customized Service Offer
n/aELISA Kit for Forkhead Box Protein G1 (FOXG1)ELISA Kit Customized Service Offer
  1. "Human brain factor 1, a new member of the fork head gene family."Genomics 21:551-557(1994) [PubMed] [Europe PMC] [Abstract]
  2. "The genes for human brain factor 1 and 2, members of the fork head gene family, are clustered on chromosome 14q."Biochim. Biophys. Acta 1262:105-112(1995) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Human PLU-1 has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9."J. Biol. Chem. 278:20507-20513(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Comparative evolutionary analysis of the FoxG1 transcription factor from diverse vertebrates identifies conserved recognition sites for microRNA regulation."Dev. Genes Evol. 217:227-233(2007) [PubMed] [Europe PMC] [Abstract]
  7. "A missense mutation within the fork-head domain of the forkhead box G1 Gene (FOXG1) affects its nuclear localization."Hum. Mutat. 32:E2026-E2035(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Novel FOXG1 mutations associated with the congenital variant of Rett syndrome."J. Med. Genet. 47:49-53(2010) [PubMed] [Europe PMC] [Abstract]